Synergysm of voriconazole or itraconazole with other antifungal agents against species of Fusarium
TB Spader, TP Venturini, L Rossato, LB Denardi… - Revista iberoamericana …, 2013 - Elsevier
Abstract Background Infections caused by Fusarium are difficult to treat because these fungi
show in vitro and in vivo resistance to practically all the antifungal agents available, which
explains the high mortality rates. An attempt to overcome fungal resistance is the
combination of antifungal agents, especially those with different mechanisms of action. Aims
Evaluate the in vitro interactions of combinations of voriconazole or itraconazole with other
antifungal agents against 32 isolates of Fusarium spp.: Fusarium chlamydosporum …
show in vitro and in vivo resistance to practically all the antifungal agents available, which
explains the high mortality rates. An attempt to overcome fungal resistance is the
combination of antifungal agents, especially those with different mechanisms of action. Aims
Evaluate the in vitro interactions of combinations of voriconazole or itraconazole with other
antifungal agents against 32 isolates of Fusarium spp.: Fusarium chlamydosporum …
