Systemic mastocytosis accompanied by a non-secretory plasma cell dyscrasia and nephrotic syndrome-level proteinuria in a 76-year-old patient

V Papadopoulou, S Ioannou, G Levidou, E Variami… - Acta …, 2014 - karger.com
V Papadopoulou, S Ioannou, G Levidou, E Variami, P Kouzis, M Siakantaris
Acta Haematologica, 2014karger.com
We report here the interesting case of a 76-year-old man with severe proteinuria who was
diagnosed with systemic mastocytosis accompanied by a clonal non-mast-cell lineage
haematological disorder (a non-secretory plasma cell dyscrasia). This is a unique report of
systemic mastocytosis with a non-secretory plasma cell dyscrasia and nephrotic syndrome.
The pathophysiological relevance between these entities along with the probability of occult
amyloidosis is discussed.
Abstract
We report here the interesting case of a 76-year-old man with severe proteinuria who was diagnosed with systemic mastocytosis accompanied by a clonal non-mast-cell lineage haematological disorder (a non-secretory plasma cell dyscrasia). This is a unique report of systemic mastocytosis with a non-secretory plasma cell dyscrasia and nephrotic syndrome. The pathophysiological relevance between these entities along with the probability of occult amyloidosis is discussed.
Karger
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