TLR-9 promoter polymorphisms (T-1237C and T-1486C) are not associated with systemic lupus erythematosus: a case control study and meta-analysis
AK Panda, SS Pattanaik, R Tripathy, BK Das - Human Immunology, 2013 - Elsevier
Toll like receptors (TLRs) are essential molecules implicated in both innate and adaptive
immune response. Polymorphisms in TLR gene have been associated with various
infectious diseases and autoimmune disorders. Role of TLR9 has been elegantly
demonstrated in both human systemic lupus erythematosus (SLE) and mice model of lupus.
In the present study we investigated association of TLR-9 promoter polymorphisms (T-
1237C and T-1486C) with susceptibility/resistance to SLE in an Eastern Indian state which is …
immune response. Polymorphisms in TLR gene have been associated with various
infectious diseases and autoimmune disorders. Role of TLR9 has been elegantly
demonstrated in both human systemic lupus erythematosus (SLE) and mice model of lupus.
In the present study we investigated association of TLR-9 promoter polymorphisms (T-
1237C and T-1486C) with susceptibility/resistance to SLE in an Eastern Indian state which is …
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