The GTPase Rab4 Interacts with Chlamydia trachomatis Inclusion Membrane Protein CT229
KA Rzomp, AR Moorhead, MA Scidmore - Infection and immunity, 2006 - Am Soc Microbiol
Chlamydiae, which are obligate intracellular bacteria, replicate in a nonlysosomal vacuole,
termed an inclusion. Although neither the host nor the chlamydial proteins that mediate the
intracellular trafficking of the inclusion have been clearly identified, several enhanced green
fluorescent protein (GFP)-tagged Rab GTPases, including Rab4A, are recruited to
chlamydial inclusions. GFP-Rab4A associates with inclusions in a species-independent
fashion by 2 h postinfection by mechanisms that have not yet been elucidated. To test …
termed an inclusion. Although neither the host nor the chlamydial proteins that mediate the
intracellular trafficking of the inclusion have been clearly identified, several enhanced green
fluorescent protein (GFP)-tagged Rab GTPases, including Rab4A, are recruited to
chlamydial inclusions. GFP-Rab4A associates with inclusions in a species-independent
fashion by 2 h postinfection by mechanisms that have not yet been elucidated. To test …
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