The biphasic expression pattern of miR-200a and E-cadherin in epithelial ovarian cancer and its correlation with clinicopathological features
Epithelial ovarian cancer (EOC) is the leading cause of death among gynecologic
malignancies. Despite great efforts to improve early detection and optimize
chemotherapeutic regimens, the 5-year survival rate is only 30% for patients presenting with
late-stage ovarian cancer. The high mortality of this disease is due to late diagnosis in over
70% of ovarian cancer cases. A class of small noncoding RNAs, or microRNAs, was found to
regulate gene expression at the post-transcriptional level. Some, but not all, of the data …
malignancies. Despite great efforts to improve early detection and optimize
chemotherapeutic regimens, the 5-year survival rate is only 30% for patients presenting with
late-stage ovarian cancer. The high mortality of this disease is due to late diagnosis in over
70% of ovarian cancer cases. A class of small noncoding RNAs, or microRNAs, was found to
regulate gene expression at the post-transcriptional level. Some, but not all, of the data …
[PDF][PDF] The Biphasic Expression Pattern of miR-200a and E-cadherin in Epithelial Ovarian
PX Shaohua Xu, W Wu, Y Ou, J Xu, G Zhang, J Li - researchgate.net
Epithelial ovarian cancer (EOC) is the leading cause of death among gynecologic
malignancies. Despite great efforts to improve early detection and optimize
chemotherapeutic regimens, the 5-year survival rate is only 30% for patients presenting with
late-stage ovarian cancer. The high mortality of this disease is due to late diagnosis in over
70% of ovarian cancer cases. A class of small noncoding RNAs, or microRNAs, was found to
regulate gene expression at the post-transcriptional level. Some, but not all, of the data …
malignancies. Despite great efforts to improve early detection and optimize
chemotherapeutic regimens, the 5-year survival rate is only 30% for patients presenting with
late-stage ovarian cancer. The high mortality of this disease is due to late diagnosis in over
70% of ovarian cancer cases. A class of small noncoding RNAs, or microRNAs, was found to
regulate gene expression at the post-transcriptional level. Some, but not all, of the data …
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