The cell wall protein Rhd3/Pga29 is over-expressed in Candida albicans upon micafungin treatment

E Vavala, G Mignogna, F Spano, A Stringaro… - Journal of …, 2013 - Taylor & Francis
Candida albicans cell wall constitutes a sensitive boundary that undergoes molecular
changes upon environmental injuries. Antimycotics exert an intense action on cell wall
eliciting both qualitative and quantitative changes of resident proteins. The emergence of
drug resistance is marked by a modulation of cell wall proteomic profile. In this study, we
monitored, at the proteome level through a two-dimensional gel electrophoresis-based
approach, differences of cell wall proteins in sensitive and resistant strains of C. albicans …

The cell wall protein Rhd3/Pga29 is over-expressed in Candida albicans upon micafungin treatment.

V Elisabetta, M Giuseppina, S Furio, S Annarita… - 2013 - cabidigitallibrary.org
Candida albicans cell wall constitutes a sensitive boundary that undergoes molecular
changes upon environmental injuries. Antimycotics exert an intense action on cell wall
eliciting both qualitative and quantitative changes of resident proteins. The emergence of
drug resistance is marked by a modulation of cell wall proteomic profile. In this study, we
monitored, at the proteome level through a two-dimensional gel electrophoresis-based
approach, differences of cell wall proteins in sensitive and resistant strains of C. albicans …
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Bibliography

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