The detection and comparison of the genotoxic effects of some nitro aromatic compounds by the umu and SOS chromotest systems
K Öztürk, M Durusoy - Toxicology letters, 1999 - Elsevier
Four nitroarenes were tested in two standard genotoxicity assay systems using three well-
known bacterial tester strains. The results were as follows: 4-nitroquinoline 1-oxide (4NQO)
was positive in Quillardet and Hofnung's SOS chromotest using Escherichia coli strain PQ37
both in the presence and absence of microsomal (S9) supplements and in the Salmonella
typhimurium umu tester strains NM2009 and NM3009, which express high levels of O-
acetyltransferase (O-AT) and O-AT plus nitroreductase (NR) respectively. m-Nitrocinnamic …
known bacterial tester strains. The results were as follows: 4-nitroquinoline 1-oxide (4NQO)
was positive in Quillardet and Hofnung's SOS chromotest using Escherichia coli strain PQ37
both in the presence and absence of microsomal (S9) supplements and in the Salmonella
typhimurium umu tester strains NM2009 and NM3009, which express high levels of O-
acetyltransferase (O-AT) and O-AT plus nitroreductase (NR) respectively. m-Nitrocinnamic …
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