The functional significance of the TGM2 gene in schizophrenia: a correlation of SNPs and circulating IL-2 levels

M Bradford, MH Law, IL Megson, J Wei - Journal of Neuroimmunology, 2011 - Elsevier
The present study was undertaken to genotype four single nucleotide polymorphisms, which
were previously found to be associated with schizophrenia, in 77 patients with
schizophrenia and 52 control subjects in order to assess their genotypic association with
plasma IL-2 levels. Kruskal–Wallis analysis revealed an association between rs4811528
and plasma IL-2 levels in the patient group (χ2= 7.60, df= 2, p= 0.022) but not in the control
group; binary logistic regression also confirmed the association of rs4811528 with altered IL …
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