Alcoholism plays a major role in the insufficient utilization or deficiency of the vitamin B-
complex molecules, and the pathologies resulting therefrom. Thiamine, pyridoxamine, and
folic acid, each contain primary amine functional groups, whereas nicotinamide and vitamin
B 12 contain amide groups, each of which are potential reactants with acetaldehyde (AcH),
the primary intermediate in the metabolism of ethanol. In this current study, it is reported that
prothrombin time (PT), which is prolonged in a fraction of the alcoholic population, can be …