The maintenance of single-locus polymorphism. I. Numerical studies of a viability selection model.

HG Spencer, RW Marks - Genetics, 1988 - academic.oup.com
The ability of viability selection to maintain single-locus polymorphism is investigated with
two models in which the population is bombarded with a series of mutations with random
fitnesses. In the first model, the population is allowed to reach equilibrium before mutation
resumes; in the second the iterations and mutation occur simultaneously. Monte Carlo
simulations of these models show that viability selection is easily able to maintain stable 6-or
7-allele polymorphisms and that monomorphisms and diallelic polymorphisms are …
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