The novel diagnostic marker in low-LVEF heart failure patients.

S Demir, H Ede, M Kaplan, F Yavuz… - Bratislavske Lekarske …, 2018 - europepmc.org
S Demir, H Ede, M Kaplan, F Yavuz, C Yucel, IH Kurt
Bratislavske Lekarske Listy, 2018europepmc.org
Objective The structural and compositional changes in the myocardium seem to have a
major role in the development of heart failure (HF). Imbalance between production and
degradation in extracellular collagen results in increase of collagen synthesis biomarkers in
the circulation as the carboxy-terminal propeptide of type I procollagen (PIP). Here we aimed
to determine role of PIP in the diagnosis of chronic HF.
Objective
The structural and compositional changes in the myocardium seem to have a major role in the development of heart failure (HF). Imbalance between production and degradation in extracellular collagen results in increase of collagen synthesis biomarkers in the circulation as the carboxy-terminal propeptide of type I procollagen (PIP). Here we aimed to determine role of PIP in the diagnosis of chronic HF.
europepmc.org
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