Purpose Thiamine functions as an important cofactor in aerobic metabolism and thiamine
deficiency can contribute to lactic acidosis. Although increased rates of thiamine deficiency
have been described in diabetic outpatients, this phenomenon has not been studied in
relation to diabetic ketoacidosis (DKA). In the present study, we hypothesize that thiamine
deficiency is associated with elevated lactate in patients with DKA. Materials and Methods
This was a prospective observational study of patients presenting to a tertiary care center …