… VEGF-C. Our objective was to determine the role of the lymphatic system and VEGF-C for
lymphogenic metastasis in prostate cancer. Unlike the influence of blood …

… [ 4 5 ] Detection of lymphatic vessels is reliably accomplished by immunohistochemistry …
of the vascular endothelial growth factor-C (VEGF-C) in relation to the mean LVD and lymph …

… factor, vascular endothelial growth factor C (VEGF-C). Increased … importance of the lymphatic
system is not restricted to tumor … to the formation of lymphogenic metastases.” This opinion …

… growth factors in prostate cancer and their important contribution to lymphangiogenesis in
prostate cancer lymph node metastasis… prostate cancer cells to enter into the lymphatic vessels…

… Vascular endothelial growth factor-C (VEGF-C) and VEGF receptor 3 signaling … metastasize
through the lymphatic vessels, for example, the fibrosarcoma T241 and the prostate cancer …

… We have revealed that the formation of new lymphatic vessels is closely related to metastasis.
We provide strong evidence that TAMs induce lymphangiogenesis in the peritumoral …

… , including breast cancer, prostate cancer, and melanoma (9, … -C activity by shRNA silencing,
sVEGFR-3-Ig, or function-… with metastases, new lymphatic vessels were formed only in their …

… lymphatic vessels, or by the de novo formation of lymphatic … al., 2002), and vascular endothelial
growth factor receptor-3 (… TRAMP-C syngeneic transplantation model of prostate cancer) …

… on the role of both blood and lymphatic vessels in cancer cell metastasis is summarized.
In … , in the presence of specific growth factors undergo trans-differentiation into …

… for lymphatic vessels or pro-lymphangiogenic growth factors … may suffice to support
lymphogenic spread of tumor cells in … of the vascular endothelial growth factor receptor family that …