Transcriptional responses of Candida glabrata biofilm cells to fluconazole are modulated by the carbon source

R Alves, SL Kastora, A Gomes-Gonçalves… - npj Biofilms and …, 2020 - nature.com
… grown only in the presence of glucose exhibit the same transcriptional pattern of regulation
for … that these transcriptional responses to fluconazole are independent of the carbon source. …

Physiologically relevant alternative carbon sources modulate biofilm formation, cell wall architecture, and the stress and antifungal resistance of Candida glabrata

SY Chew, KL Ho, YK Cheah, D Sandai… - International journal of …, 2019 - mdpi.com
… that assimilate acetate are more susceptible to fluconazole, albeit in the presence of glucose…
of the transcription factors Msn2 and Msn4 [46,47]. Candida glabrata has been reported to …

Decoding the role of oxidative stress resistance and alternative carbon substrate assimilation in the mature biofilm growth mode of Candida glabrata

K Raj, D Paul, P Rishi, G Shukla, D Dhotre… - BMC microbiology, 2024 - Springer
glabrata (NCCPF-100,037) in biofilm stage modulates its … in the media in presence of
fluconazole, metal stress inducer (… role of CgPCK1 in alternative carbon source assimilation and …

Function and regulation of Candida albicans and C. glabrata carboxylic acid transporters and their Role in biofilm formation, antifungal drug resistance and …

RMA Alves - 2020 - repositorium.sdum.uminho.pt
… and phagocytosis in Candida glabrata are modulated by the carbon source. 33rd SMYTE -
… how acetate modulates the transcriptional responses of C. glabrata biofilms to fluconazole, …

Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate

S Mota, R Alves, C Carneiro, S Silva… - Frontiers in …, 2015 - frontiersin.org
… In addition, we studied the effect of fluconazole in C. glabrata pre-grown biofilms in the …
the view that adaptative responses of Candida cells to the types of carbon source present in …

Transcriptomic and proteomic profiling revealed reprogramming of carbon metabolism in acetate-grown human pathogen Candida glabrata

SY Chew, AJP Brown, BYC Lau, YK Cheah… - Journal of Biomedical …, 2021 - Springer
glabrata renders the cells to be more sensitive to fluconazole … this goal, we examined the
transcriptional response of C. … transcriptional regulation in order to modulate fitness attributes of …

The carboxylic acid transporters Jen1 and Jen2 affect the architecture and fluconazole susceptibility of Candida albicans biofilm in the presence of lactate

R Alves, S Mota, S Silva, C F. Rodrigues, AJ P. Brown… - Biofouling, 2017 - Taylor & Francis
… view that the adaptation of Candida cells to the carbon source present in the host … carbon
source, biofilms formed in the presence of lactate developed different structures and the cells

Candida glabrata Antifungal Resistance and Virulence Factors, a Perfect Pathogenic Combination

…, E Ocharán-Hernández, C Rodríguez-Cerdeira… - Pharmaceutics, 2021 - mdpi.com
… The study concluded that both genes are needed to modulate the … glabrata sensu stricto is
more susceptible to fluconazole, … glabrata complex are biofilm formation and the production of …

Possible Contribution of Alternative Transcript Isoforms in Mature Biofilm Growth Phase of Candida glabrata

K Raj, P Rishi, G Shukla, SM Rudramurhty… - Indian Journal of …, 2022 - Springer
… genes showed significant DTU in the mature biofilm cells. Gene ontology, pathway analysis
… is required for transitioning the planktonic cells to biofilm in C. glabrata. The present study …

[HTML][HTML] Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality

K Lagree, CA Woolford, MY Huang, G May… - PLoS …, 2020 - journals.plos.org
… that drives the transcriptional response of C. albicans to … repression activities are modulated
by carbon source, our RNA-… to the ergosterol synthesis inhibitor fluconazole (Fig 6A). These …