Transfection of antisense p38α gene ameliorates myocardial cell injury mediated by hypoxia and burn serum
Y Huang, J Zheng, P Fan, X Zhang - Burns, 2007 - Elsevier
BACKGROUD: Myocardial damage occurs immediately following severe burns even before
significant reduction in blood volume. This phenomenon is called postburn “shock
heart”(“cardiac shock”), the pathogenesis of which is unclear. This study was designed to
investigate the role of antisense p38α gene transfection in ameliorating hypoxia and burn
serum-mediated myocardial cell injury. METHODS: A model of myocardial cells cultured
under hypoxia and with burn serum was established. The cells were divided into control …
significant reduction in blood volume. This phenomenon is called postburn “shock
heart”(“cardiac shock”), the pathogenesis of which is unclear. This study was designed to
investigate the role of antisense p38α gene transfection in ameliorating hypoxia and burn
serum-mediated myocardial cell injury. METHODS: A model of myocardial cells cultured
under hypoxia and with burn serum was established. The cells were divided into control …
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