Tumour surveillance in Beckwith–Wiedemann syndrome and hemihyperplasia: a critical review of the evidence and suggested guidelines for local practice
There is strong evidence for an association between overgrowth disorders such as Beckwith–
Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also
been observed in individuals with isolated hemihyperplasia. We critically review the
evidence for tumour surveillance in Beckwith–Wiedemann syndrome and isolated
hemihyperplasia and suggest local practice guidelines.
Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also
been observed in individuals with isolated hemihyperplasia. We critically review the
evidence for tumour surveillance in Beckwith–Wiedemann syndrome and isolated
hemihyperplasia and suggest local practice guidelines.
Abstract
There is strong evidence for an association between overgrowth disorders such as Beckwith–Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also been observed in individuals with isolated hemihyperplasia. We critically review the evidence for tumour surveillance in Beckwith–Wiedemann syndrome and isolated hemihyperplasia and suggest local practice guidelines.
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