Two new 2-arylbenzofuran derivatives from hypoglycemic activity-bearing fractions of Morus insignis
P Basnet, S Kadota, S Terashima… - Chemical and …, 1993 - jstage.jst.go.jp
P Basnet, S Kadota, S Terashima, M SHIMIZU, T Namba
Chemical and pharmaceutical bulletin, 1993•jstage.jst.go.jp抄録 Ethyl acetate-and n-butanol-soluble fractions of the leaves of Morus insignis showed a
significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From
these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2)
and moracin M-3'-O-β-D-glucopyranoside (3) were isolated, along with six known
compounds [β-sitosterol, β-sitosterol-3-O-β-glucopyranoside, ursolic acid, moracin M (1),
kaempferol-3-O-β-glucopyranoside and quercetin-3-O-β-glucopyranoside] and the …
significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From
these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2)
and moracin M-3'-O-β-D-glucopyranoside (3) were isolated, along with six known
compounds [β-sitosterol, β-sitosterol-3-O-β-glucopyranoside, ursolic acid, moracin M (1),
kaempferol-3-O-β-glucopyranoside and quercetin-3-O-β-glucopyranoside] and the …
抄録
Ethyl acetate-and n-butanol-soluble fractions of the leaves of Morus insignis showed a significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From these hypoglycemic activity-showing fractions, two new compounds, mulberrofuran U (2) and moracin M-3'-O-β-D-glucopyranoside (3) were isolated, along with six known compounds [β-sitosterol, β-sitosterol-3-O-β-glucopyranoside, ursolic acid, moracin M (1), kaempferol-3-O-β-glucopyranoside and quercetin-3-O-β-glucopyranoside] and the structures of the new compounds were determined by spectroscopic and chemical methods.
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