Ultrastructural pathology of Creutzfeldt-Jakob disease and fatal familial insomnia.
PP Liberski, P Giraud, N Kopp - Folia Neuropathologica, 2000 - europepmc.org
PP Liberski, P Giraud, N Kopp
Folia Neuropathologica, 2000•europepmc.orgIn this study we examined well fixed brain biopsies of 9 sporadic CJD, 9 iatrogenic CJD
cases, 2 hereditary CJD (Gly200Lys and Val203Iso), a case of vCJD and a case of fatal
familial insomnia (FFI) from a new French family collected over the years at the Service de
Neuropathologie, Hopital Neurologique, Lyon, France. Tubulovesicular structures (TVS)
were found in every case including FFI and nvCJD. Thus, TVS, as we suggested previously
are important pathologic structure which significance should be more extensively studied.
cases, 2 hereditary CJD (Gly200Lys and Val203Iso), a case of vCJD and a case of fatal
familial insomnia (FFI) from a new French family collected over the years at the Service de
Neuropathologie, Hopital Neurologique, Lyon, France. Tubulovesicular structures (TVS)
were found in every case including FFI and nvCJD. Thus, TVS, as we suggested previously
are important pathologic structure which significance should be more extensively studied.
In this study we examined well fixed brain biopsies of 9 sporadic CJD, 9 iatrogenic CJD cases, 2 hereditary CJD (Gly200Lys and Val203Iso), a case of vCJD and a case of fatal familial insomnia (FFI) from a new French family collected over the years at the Service de Neuropathologie, Hopital Neurologique, Lyon, France. Tubulovesicular structures (TVS) were found in every case including FFI and nvCJD. Thus, TVS, as we suggested previously are important pathologic structure which significance should be more extensively studied.
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