Up-regulation of Che-1 relates to neuronal apoptosis after traumatic brain injury in adult rats

J Xu, W Jin, X Wu, X Wu, A Li, K Ke, J Cao, X Liu… - Cellular and molecular …, 2013 - Springer
… lesion model in adult rats. In the present study, DNA damage and up-regulation of Che-1
protein levels were observed in ipsilateral brain cortex after injury. The temporal changes of …

Che-1 inhibits oxygen–glucose deprivation/reoxygenation-induced neuronal apoptosis associated with inhibition of the p53-mediated proapoptotic signaling pathway

S Guo, R Chen, X Chen, Z Xie, F Huo, Z Wu - Neuroreport, 2018 - journals.lww.com
… that Che-1 is increased after traumatic brain injury in adult rats and is associated with neuronal
apoptosis 33 . … -related neuronal apoptosis remains unclear. In this study, we found that …

Che-1 participates in the regulation of rat cortical neuronal apoptosis and axonal regeneration after traumatic brain injury via p53

AH Li, AS Guo, X Chen, XL Sun - Zhonghua yi xue za zhi, 2013 - europepmc.org
… of Che-1 peaked at Day 3 post-injury (0.817 ± 0.022, P < 0.05) and it was related with neuronal
apoptosis. … of p53, GAP43 and active-caspase-3 were associated with the level of Che-1. …

Apoptosis after traumatic brain injury

R Raghupathi, DI Graham, TK McINTOSH - Journal of neurotrauma, 2000 - liebertpub.com
Apoptosis of neurons and glia contribute to the overall … of traumatic brain injury (TBI) in both
humans and animals. In both head-injured humans and following experimental brain injury, …

Heterozygous Che-1 KO mice show deficiencies in object recognition memory persistence

G Zalcman, N Corbi, MG Di Certo, E Mattei… - Neuroscience …, 2016 - Elsevier
… Its rat and mouse homologous proteins are AATF (apoptosis … -apoptotic activity after traumatic
brain injury, during neuronal … Most of the work done with Che-1 protein is linked to cancer …

A Role for the p75NTR in Axonal Degeneration and Apoptosis Induced by Oxidative Stress

BR Kraemer - 2014 - ir.vanderbilt.edu
… in transcriptional up-regulation of an array of pro-apoptotic genes… produced and secreted in
vivo after brain injury. In the cortex … on neuronal survival in our culture system, rat sympathetic …

[PDF][PDF] Che-1 通过mTOR 通路调控自噬在谷氨酸所致神经元损伤中的作用研究

郭生龙, 朱洁, 谢瑱, 李鹏, 费裕朗… - 现代生物医学 …, 2019 - biomed.cnjournals.com
… Ginsenoside Rb2 suppresses the glutamate-mediated oxidative stress and neuronal cell
death in … Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke[J]. …

[PDF][PDF] 急性心肌梗死合并肺部感染患者多药耐药菌分布特征及心肌酶谱指标与炎性因子的关系分析

段玉彩, 魏亚君, 郭玲, 赵瑞, 王丽 - Proteus, 2019 - biomed.cnjournals.com
… complicated with pulmonary infection is closely related to the level of inflammatory factors, …
Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis