Variability of the response to activated protein C during normal pregnancy
MI Bokarewa, M Wramsby, K Bremme… - Blood coagulation & …, 1997 - journals.lww.com
The response to activated protein C (APC) was investigated in 28 healthy women, non-
carriers of the Arg 506-Gln mutation in factor V, throughout pregnancy (gestation weeks 12,
20, 28, 32 and 37) and after the delivery. A suppression of APC response was observed
which reached lowest values by week 28 (nAPC-ratio 0.78±0.13), sustained low up to the
end of pregnancy and rose after delivery (1.11±0.22; P< 0.05). APC resistance (nAPC ratio<
0.75) was registered in 16 of the 28 women (57%). A reduction of APC ratio was directly …
carriers of the Arg 506-Gln mutation in factor V, throughout pregnancy (gestation weeks 12,
20, 28, 32 and 37) and after the delivery. A suppression of APC response was observed
which reached lowest values by week 28 (nAPC-ratio 0.78±0.13), sustained low up to the
end of pregnancy and rose after delivery (1.11±0.22; P< 0.05). APC resistance (nAPC ratio<
0.75) was registered in 16 of the 28 women (57%). A reduction of APC ratio was directly …
以上显示的是最相近的搜索结果。 查看全部搜索结果