Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis

H Mehta, HB Mehta, P Garg… - Indian journal of …, 2008 - journals.lww.com
We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic
female who did not respond to standard antifungal treatment. She was started on topical
natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and
systemic ketoconazole was added, however, there was no response and the infiltrate
increased further. She was then switched to topical and systemic voriconazole. Steady
resolution of the infiltrate was noted within 2 weeks of therapy.

Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis.

HM Hijab Mehta, HB Mehta, PG Prashant Garg… - 2008 - cabidigitallibrary.org
A case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female
who did not respond to standard antifungal treatment is described [India]. She was started
on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin
B and systemic ketoconazole (Vfend) were added to her treatment; however, there was no
response and the infiltrate increased further. She was then switched to topical and systemic
voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy.
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