Development, Strategies, and Challenges for Tularemia Vaccine

S Moradkasani, M Maurin, AS Farrokhi, S Esmaeili - Current Microbiology, 2024 - Springer
Francisella tularensis is a facultative intracellular bacterial pathogen that affects both
humans and animals. It was developed into a biological warfare weapon as a result. In this …

Vaccines Against Francisella Tularensis

J Wayne Conlan, PCF Oyston - … of the New York Academy of …, 2007 - Wiley Online Library
Francisella tularensis is one of the most pathogenic pathogens known, especially when
disseminated as a small particle aerosol. Because of this, it was developed into a biological …

Tularemia vaccines: recent developments and remaining hurdles

JW Conlan - Future microbiology, 2011 - Future Medicine
Francisella tularensis subsp. tularensis is a facultative intracellular bacterial pathogen of
humans and other mammals. Its inhaled infectious dose is very low and can result in very …

[HTML][HTML] Tularemia vaccines

D Putzova, I Senitkova, J Stulik - Folia microbiologica, 2016 - Springer
Francisella tularensis is the causative agent of the potentially lethal disease tularemia. Due
to a low infectious dose and ease of airborne transmission, Francisella is classified as a …

Tularemia vaccine: past, present and future

PCF Oyston, JE Quarry - Antonie Van Leeuwenhoek, 2005 - Springer
Francisella tularensis is a Gram negative intracellular pathogen that causes the highly
debilitating or fatal disease tularemia. F. tularensis can infect a wide range of animals and …

Rationally designed tularemia vaccines

BJ Mann, NM Ark - Expert review of vaccines, 2009 - Taylor & Francis
Tularemia, caused by the Gram-negative bacterium Francisella tularensis, can be contracted
by the bite of an arthropod vector or by inhalation. This disease occurs relatively infrequently …

[HTML][HTML] Current status of vaccine development for tularemia preparedness

KJ Hong, PG Park, SH Seo, G Rhie… - Clinical and …, 2013 - synapse.koreamed.org
Tularemia is a high-risk infectious disease caused by Gram-negative bacterium Francisella
tularensis. Due to its high fatality at very low colony-forming units (less than 10), F. tularensis …

Vaccines against tularemia

EM Barry, L Cole, AE Santiago - Human vaccines, 2009 - Taylor & Francis
Francisella tularensis is a Category A select agent for which vaccine and countermeasure
development are a priority. In the past 8 years, renewed interest in this pathogen has led to …

Vaccines and therapeutic agents for tularemia

R KuoLee, W Chen - Expert Opinion on Therapeutic Patents, 2007 - Taylor & Francis
Tularemia is not particularly prevalent in North America under normal circumstances;
however, recent concerns about bioterrorism have brought Francisella tularensis, the …

Tularemia vaccine development: paralysis or progress?

R Sunagar, S Kumar, BJ Franz… - … development and therapy, 2016 - Taylor & Francis
Francisella tularensis (Ft) is a gram-negative intercellular pathogen and category A biothreat
agent. However, despite 15 years of strong government investment and intense research …