Under hypercholesterolemic conditions, exposure of cells to lipoproteins results in a subtle
membrane increase in the levels of cholesterol and 7-ketocholesterol, as compared to …

Cholesterol renders mammalian cell membranes more compact by reducing the amount of
voids in the membrane structure. Because of this, cholesterol is known to regulate the ability …

Cholesterol regulates the function of membrane proteins either via direct or membrane-
mediated effects. Therefore, its ready availability is crucial for many protein-governed …

Cholesterol is a necessary component and critical regulator of liquid‐ordered membrane
domains. However, the structural features that determine its unique physicochemical …

Intermolecular interactions between cholesterol and lipids in cell membranes, which play
critical roles in cellular processes such as the formation of nano-domains, depend on the …

Side-chain oxysterols are enzymatically generated oxidation products of cholesterol that
serve a central role in mediating cholesterol homeostasis. Recent work has shown that side …

Cholesterol is an essential component of all animal cell membranes and plays an important
role in maintaining the membrane structure and physical–chemical properties necessary for …

The function of living systems is inherently based on cells, which are the key building blocks
of living organisms. Each cell in a human body is surrounded by a cell membrane, which …

Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their
interactions are crucial in ether lipid mediated cholesterol trafficking. We report on …

The plasma membrane is a highly complex multicomponent system that is central to the
functioning of cells. Cholesterol, a key lipid component of the plasma membrane, promotes …