Ca2+, as a second messenger in cells, enables organisms to adapt to different
environmental stresses by rapidly sensing and responding to external stimuli. In recent …

The calcineurin-CRZ1 signaling pathway is conserved from yeasts to humans, and is
involved in survival, tolerance to biotic and abiotic stress conditions, virulence, and drug …

Calcium signaling systems are widely employed in eukaryotes and are implicated in the
regulation of diverse biological processes. Calcineurin is an important signaling component …

The calcineurin pathway is a critical signal transduction pathway in fungi that mediates
growth, morphology, stress responses, and pathogenicity. The importance of the calcineurin …

Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific
protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus …

Abstract In fungi, the Ca 2+/calcineurin signaling pathway is critical in mediating growth,
morphology, stress responses, and pathogenicity. Crz1 is a calcineurin-responsive zinc …

Ca2+/calmodulin-dependent phosphatase calcineurin is one of the important regulators of
intracellular calcium homeostasis and has been investigated extensively in Saccharomyces …

ABSTRACT Calcium (Ca2+) is a universal signalling molecule of life. The Ca2+ signalling is
an evolutionarily conserved process from prokaryotes to eukaryotes. Ca2+ at high …

Background Calcineurin, a serine/threonine-specific protein phosphatase, plays an
important role in the control of cell morphology and virulence in fungi. Calcineurin regulates …

The protein phosphatase calcineurin is an important mediator connecting calcium‐
dependent signalling to various cellular responses in multiple organisms. In fungi …