Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic …
MA Cohn, I Hjelmsø, LC Wu, P Guldberg… - Nucleic acids …, 2001 - academic.oup.com
Abstract The mts1/S100A4 gene encodes a small acidic calcium-binding protein that is
expressed in a cell-specific manner in development, tumorigenesis and certain tissues of …
expressed in a cell-specific manner in development, tumorigenesis and certain tissues of …
[HTML][HTML] The κB and V (D) J Recombination Signal Sequence Binding ProteinKRC Regulates Transcription of the Mouse Metastasis-associated Gene S100A4/mts1
I Hjelmsoe, CE Allen, MA Cohn, EM Tulchinsky… - Journal of Biological …, 2000 - ASBMB
A κB-like sequence, Sb, is integral to the composite enhancer located in the first intron of the
metastasis-associated gene, S100A4/mts1. Oligonucleotides containing this sequence form …
metastasis-associated gene, S100A4/mts1. Oligonucleotides containing this sequence form …
[HTML][HTML] Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor
D Chen, MPA Davies, PS Rudland… - Journal of Biological …, 1997 - ASBMB
The S100-related calcium-binding protein S100A4 (p9Ka) is expressed at a low level in rat
mammary epithelial cells from normal mammary gland and benign mammary tumors. In …
mammary epithelial cells from normal mammary gland and benign mammary tumors. In …
Expression of Mts1, a metastasis-associated gene, increases motility but not invasion of a nonmetastatic mouse mammary adenocarcinoma cell line.
HL Ford, MM Salim, R Chakravarty, V Aluiddin, SB Zain - Oncogene, 1995 - europepmc.org
The mts1 gene codes for a 101 amino acid protein belonging to the S100 subfamily of Ca
(2+)-binding proteins. Mts1 is overexpressed in metastatic cancers as compared to their …
(2+)-binding proteins. Mts1 is overexpressed in metastatic cancers as compared to their …
A minisatellite “core” element constitutes a novel, chromatin-specific activator of mts1 gene transcription
EB Prokhortchouk, AV Prokhortchouk… - Journal of molecular …, 1998 - Elsevier
Expression of the mts1 gene is often associated with malignant transformation of tumor cells.
Transcription of the gene is controlled by a number of positive and negative regulatory …
Transcription of the gene is controlled by a number of positive and negative regulatory …
[HTML][HTML] Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction
M Grigorian, S Andresen, E Tulchinsky… - Journal of Biological …, 2001 - ASBMB
A physical and functional interaction between the Ca 2+-binding protein Mts1 (S100A4) and
the tumor suppressor p53 protein is shown here for the first time. We demonstrate that Mts1 …
the tumor suppressor p53 protein is shown here for the first time. We demonstrate that Mts1 …
Characterization of a Splice Variant of Metastasis-Associated h-mtsl (S100A4) Gene Expressed in Human Infiltrating Carcinomas of the Breast
E Albertazzi, F Cajone, GV Sherbet - DNA and cell biology, 1998 - liebertpub.com
The h-mtsl (S100A4) is a member of the S100 gene family, coding for a calcium-binding
protein. It is a metastasis-associated gene whose expression shows strong correlation with …
protein. It is a metastasis-associated gene whose expression shows strong correlation with …
Expression of Metastasis-Associated Genes h-mts1 (S100A4) and nm23 in Carcinoma of Breast Is Related to Disease Progression
E Albertazzi, F Cajone, BE Leone, RNG Naguib… - DNA and cell …, 1998 - liebertpub.com
The murine 18A2/mts1 and its human homolog h-mts1 (S100A4), encoding a Ca2+-binding
protein belonging to the S-100 family, are associated with high invasive and metastatic …
protein belonging to the S-100 family, are associated with high invasive and metastatic …
Structure of gene mts1, transcribed in metastatic mouse tumor cells
EM Tulchinsky, MS Grigorian, AK Ebralidze… - Gene, 1990 - Elsevier
Different oncogenes are implicated in the genesis of tumors. However, little is known so far
about the genes which are activated at the latest stages of tumor progression. While …
about the genes which are activated at the latest stages of tumor progression. While …
Effect of mts1 (S100A4) expression on the progression of human breast cancer cells
M Grigorian, N Ambartsumian… - … journal of cancer, 1996 - Wiley Online Library
Abstract The mts1 (S100A4) gene, encoding a Ca2+‐binding protein of the S‐100 subfamily,
is involved in the control of tumor metastasis in some murine tumor cell lines. To further …
is involved in the control of tumor metastasis in some murine tumor cell lines. To further …