Continuous Renal Replacement Therapy (CRRT) is more and more widely used in patients
for various indications recent years. It is still intricate for clinicians to decide a suitable …

Acute kidney injury represents a common complication in critically ill patients affected by
septic shock and in many cases continuous renal replacement therapy (CRRT) may be …

Background Drug dosing for septic patients with acute renal failure receiving continuous
renal replacement therapy (CRRT) is complicated, and failure to correctly dose may result in …

Background: Appropriate antibacterial therapy is important to maximize patient survival in
sepsis. Acute renal failure complicates optimal antibiotic administration. Methods: MEDLINE …

Determining appropriate antibiotic dosing for critically ill patients receiving renal
replacement therapy (RRT) is complex. Worldwide unstandardized and heterogeneous …

Objectives: To outline the concepts involved in optimizing antibacterial dosing in critically ill
patients with acute renal failure undergoing continuous renal replacement therapy (CRRT) …

ABSTRACT A careful management of antimicrobials is essential in the critically ill with acute
kidney injury, especially if renal replacement therapy is required. Acute kidney injury may …

Objective: To summarize current antibiotic dosing recommendations in critically ill patients
receiving intermittent hemodialysis (IHD), prolonged intermittent renal replacement therapy …

Infectious diseases and impaired renal function often occur in critically ill patients, and
delaying the start of appropriate empiric antimicrobial therapy or starting inappropriate …

Purpose Augmented renal clearance (ARC) is common in critically ill patients and may lead
to subtherapeutic levels of antibiotics, thus influencing clinical outcomes and emergence of …