Establishment of cytochrome P450 1a gene-knockout Javanese medaka, Oryzias javanicus, which distinguishes toxicity modes of the polycyclic aromatic …
Abstract Cytochrome P450 1a (Cyp1a) is an important enzyme for metabolism of organic
pollutants. To understand its reaction to polycyclic aromatic hydrocarbons (PAHs), we …
pollutants. To understand its reaction to polycyclic aromatic hydrocarbons (PAHs), we …
Correlation between cytochrome P450 1A (cyp1a) mRNA expression and ambient phenanthrene and pyrene concentration in Javanese Medaka Oryzias javanicus
Abstract Cytochrome P450 1A (Cyp1a) catabolizes polycyclic organic compounds. In this
study, we sequenced the cyp1a gene from two Javanese medaka Oryzias javanicus strains …
study, we sequenced the cyp1a gene from two Javanese medaka Oryzias javanicus strains …
Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) …
CYP1A is involved in the metabolism of diverse chemicals, including polycyclic aromatic
hydrocarbons and alkylated-PAHs, as a first line of detoxification mechanism. First, we …
hydrocarbons and alkylated-PAHs, as a first line of detoxification mechanism. First, we …
Identification of a CYP3A-like gene and CYPs mRNA expression modulation following exposure to benzo [a] pyrene in the bivalve mollusk Chlamys farreri
S Tian, L Pan, H Zhang - Marine environmental research, 2014 - Elsevier
In this study, we isolated a CYP3A-like gene from ovary of the scallop (Chlamys farreri). High
levels of CYP3A-like gene expression occur in the digestive gland and gonad, which …
levels of CYP3A-like gene expression occur in the digestive gland and gonad, which …
Effects of benzo [a] pyrene on whole cytochrome P450-involved molecular responses in the marine medaka Oryzias melastigma
Despite being a strong toxicant for aquatic ecosystems, the effect of benzo [a] pyrene (B [a]
P) on whole cytochrome P450 (CYP) biotransformation mechanisms has not been deeply …
P) on whole cytochrome P450 (CYP) biotransformation mechanisms has not been deeply …
Three novel cytochrome P450 genes identified in the marine polychaete Perinereis nuntia and their transcriptional response to xenobiotics
S Zheng, B Chen, X Qiu, K Lin, X Yu - Aquatic toxicology, 2013 - Elsevier
Polychaetes have previously been used as bioindicators of environmental pollution. Their
ability to eliminate organic pollutants such as polycyclic aromatic hydrocarbons (PAH) has …
ability to eliminate organic pollutants such as polycyclic aromatic hydrocarbons (PAH) has …
Cytochrome P450 1C1 complementary DNA cloning, sequence analysis and constitutive expression induced by benzo-a-pyrene in Nile tilapia (Oreochromis niloticus)
AAI Hassanin, Y Kaminishi, A Funahashi, T Itakura - Aquatic toxicology, 2012 - Elsevier
CYP1C is the newest member of the CYP1 family of P450s; however, its physiological
significance, inducers, and metabolic functions are unknown. In this study, a new …
significance, inducers, and metabolic functions are unknown. In this study, a new …
Identification of two isoforms of CYP4 in Marsupenaeus japonicus and their mRNA expression profile response to benzo [a] pyrene
J Zheng, Y Mao, Y Qiao, Z Shi, Y Su, J Wang - Marine Environmental …, 2015 - Elsevier
CYP4 enzymes are essential components of cellular detoxification systems and play
important roles in monitoring persistent organic pollutants in marine environments. However …
important roles in monitoring persistent organic pollutants in marine environments. However …
cDNA cloning and expression of a xenobiotic metabolizing cytochrome P4501A (CYP1A) from the yellow catfish, Pelteobagrus fulvidraco (Siluriformes)
We cloned the full‐length cDNA sequence of xenobiotic metabolizing cytochrome P4501A
(CYP1A) gene from the yellow catfish (Pelteobagrus fulvidraco, Siluriformes, Bagridae). P …
(CYP1A) gene from the yellow catfish (Pelteobagrus fulvidraco, Siluriformes, Bagridae). P …
Basal and 3-methylcholanthrene-induced expression of cytochrome P450 1A, 1B and 1C genes in the Brazilian guppy, Poecilia vivipara
In fish there are four cytochrome P450 (CYP1) subfamilies: CYP1A, CYP1B, CYP1C, and
CYP1D. Here we cloned Poecilia vivipara CYP1A, with an inferred amino acid sequence …
CYP1D. Here we cloned Poecilia vivipara CYP1A, with an inferred amino acid sequence …