Mammary explants can be hormonally stimulated to mimic the biochemical changes that
occur during lactogenesis. Previous studies using mammary explants concluded that the …

White adipocytes in the mammary gland stroma comprise the majority of the mammary gland
mass. White adipocytes regulate numerous hormonal and metabolic processes and exhibit …

The Caenorhabditis elegans n-3 fatty acid desaturase (Fat-1) acts on a range of 18-and 20-
carbon n-6 fatty acid substrates. Transgenic female mice expressing the Fat-1 gene under …

During pregnancy and lactation, subcutaneous white adipocytes in the mouse mammary
gland transdifferentiate reversibly to milk‐secreting epithelial cells. In this study, we …

Specificity protein 1 (encoded by SP1) is a novel transcription factor important for the
regulation of lipid metabolism and the normal function of various hormones in model …

We generated a Spot 14 null mouse to assess the role of Spot 14 in de novo lipid synthesis
and report the Spot 14 null mouse exhibits a phenotype in the lactating mammary gland …

Mammary epithelial cells have recently been shown to express and secrete leptin into milk
and to accumulate triacylglycerol (TAG) in cytosol. We examined the effects on the …

Mammary explants can be hormonally stimulated to mimic the biochemical changes that
occur during lactogenesis. Previous studies using mammary explants concluded that the …

Thyroid hormone responsive spot 14 (THRSP, Spot14, S14) is a nuclear protein that
regulates milk fat synthesis. To investigate the role of THRSP in lipogenesis in the dairy cow …

The circular, reversible conversion of the mammary gland during pregnancy and involution
is a paradigm of physiological tissue plasticity. The two most prominent cell types in …