Many pyrimidine nucleoside analogues exhibit potent anti-herpesvirus activity. Analogues of
current interest in several laboratories include 5-propyl-2'-deoxyuridine, E-5-propenyl-2' …

Potential antiviral nucleoside analogs 1-beta-D-arabinofuranosylthymine, the 1-(2-deoxy-2-
fluoro-beta-D-arabinofuranosyl)-nucleosides of-5-methyluracil,-5-iodouracil,-5 …

Twenty 5-alkyl-2-thiopyrimidine nucleosides were newly synthesized and examined for
antiviral activities against herpes simplex virus (HSV), varicella-zoster virus (VZV) and …

In recent years several new antiviral compounds have been developed which offer great
promise for the specific treatment of herpesvirus infections of both medical importance, ie …

5-(2-Chloroethyl)-2'-deoxyuridine (CEDU), 5-(3-chloropropyl)-2'-deoxyuridine (CPDU), and
5-(2-chloroethyl)-2'-deoxycytidine (CEDC) were evaluated for activity against herpes …

The 5'-0-p-tolylsulfonyl derivatives of 5-chloro-, 5-bromo-, and 5-iodo-2'-deoxyuridine were
synthesized and converted into the corresponding 5-halo-5'-azido-2', 5'-dideoxyuridines (5 …

Seven arabinosyl, 2'-deoxyribosyl, and ribosyl pyrrolo [2, 3-d] pyrimidines were evaluated in
vitro for activity against human cytomegalovirus and for cytotoxicity in primary and …

In both primary rabbit kidney and human skin fibroblasts, the replication of a particular
herpes simplex virus, HSV-1 (strain KOS), is markedly inhibited by a wide variety of …

A series of 5-substituted l-(2-deoxy-2-fluoro-/3-D-arabinofuranosyl) cytosines 7a-d and their
corresponding uracils 9a-d, f were prepared by condensation of 3-0-acetyl-5-0-benzoyl-2 …

The author discusses structural interrelationships, metabolism and mechanism of action for
five classes of antiviral agents: pyrimidine nucleoside analogues, acyclic nucleoside …