Background: Dopamine (DA) signalling in the brain is necessary for feeding behaviour, and
alterations in the DA system have been linked to obesity. However, the precise role of DA in …

Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …

In 2010, Johnson and Kenny provided conclusive evidence that extended access to a
Western-style diet promotes addictive-like behavior in rats by downregulating D2 receptors …

Obesity has reached epidemic prevalence, and much research has focused on homeostatic
and nonhomeostatic mechanisms underlying overconsumption of food. Mesocorticolimbic …

Abstract Purpose of Review Animal and human studies suggest that diet-induced obesity
and plasticity in the central dopaminergic system are linked. However, it is unclear whether …

Central dopamine signaling regulates reward-related aspects of feeding behavior, and
during diet-induced obesity dopamine receptor signaling is altered. Yet, the influence of …

Dopamine (DA) signal play pivotal roles in regulating motivated behaviors, including feeding
behavior, but the role of midbrain DA neurons in modulating food intake and neural circuitry …

Obesity is typically associated with abnormal eating behaviors. Brain imaging studies in
humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating …

Dopamine (DA) signaling has been implicated in the control of energy balance and
ingestive behavior. In the present study, we sought to characterize body weight, body fat and …

The role of the dopamine D2 receptor (D2R) in regulating appetitive behavior continues to
be controversial. Earlier literature suggests that reduced D2R signaling diminishes …