Different quinazoline derivatives have showed wide spectrum of pharmacological activities.
Some 3-(arylideneamino)-phenylquinazoline-4 (3H)-ones have been reported to possess …

Abstract Novel 4-substituted-6, 7-dimethoxyquinazolines 3, 4a and 4b were synthesized via
reacting the corresponding 4-chloro derivative 2 with 2-(4-aminopiperazin-1-yl) ethanol …

Background: Prevalence of lung cancer and breast cancer is increasing worldwide. Current
therapies have certain limitations for the treatment of lung cancer and breast cancer. We …

A series of 4-aminoquinazoline derivatives is prepared by the nucleophilic substitution
reaction of 6, 7, 8-trimethoxy-4-chloroquinazoline and aryl amine. The structures of the …

(Aryl)-2-(2-chlorophenyl)-6-{2-[2-(2-chlorophenyl)-4-oxo (3-hydroquinazolin-3yl)] ethyl}-3-
hydroquinazolin-4-ones had been selected as target bio-active molecules. Several …

Quinazolinone backbone is present in a large number of bioactive substances. Since
remarkable cytotoxic activity is associated with some 4 (3H)-quinazolinones, in this study …

A new series of 4 (3 H)-quinazolinone analogs bearing 6-iodo and 2-thioether functions
were synthesized and screened for their in vitro antitumor activity. Eight compounds were …

Quinazolinones are a group of heterocyclic compounds that have important biological
activities such as cytotoxicity, anti-bacterial, and anti-fungal effects. Thiazole-containing …

Abstract A series of novel 4, 6, 7-substituted quinazoline derivatives were designed,
synthesized and evaluated for their antiproliferative activities against human cancer cell …

A series of novel quinazolinone derivatives bearing a disulfide bond were designed and
synthesized. Their in vitro antiproliferative activities were evaluated using CCK-8 assay …