Evidence-based analysis of amiodarone efficacy and safety

SJ Connolly - Circulation, 1999 - Am Heart Assoc
placebo-controlled studies. Nonetheless, amiodarone is approved for use against VT and
VF by most regulatory agencies worldwide and has a high profile as a useful drug. 21 Its …

Five-year follow-up of 589 patients treated with amiodarone

BA Weinberg, WM Miles, LS Klein, JE Bolander… - American heart …, 1993 - Elsevier
Abstract Between 1977 and 1986, 589 patients (age, 57±13 years; 464 men and 125
women) received amiodarone for ventricular fibrillation (VF; 147 patients), sustained (VT-S; …

Long-term efficacy and toxicity of high-dose amiodarone therapy for ventricular tachycardia or ventricular fibrillation

F Morady, MJ Sauve, P Malone, EN Shen… - The American Journal of …, 1983 - Elsevier
Amiodarone was administered to 154 patients who had sustained, symptomatic ventricular
tachycardia (VT)(n= 118) or a cardiac arrest (n= 36) and who were refractory to conventional …

Antiarrhythmic actions of amiodarone: a profile of a paradoxical agent

BN Singh - The American journal of cardiology, 1996 - Elsevier
Amiodarone, a complex compound with variegated electropharmacologic and
pharmacokinetic properties and an equally complex side-effect profile, continues to have a …

Clinical efficacy of amiodarone in treatment of recurrent ventricular tachycardia and ventricular fibrillation

JJ Heger, EN Prystowsky, DP Zipes - American Heart Journal, 1983 - Elsevier
The clinical antiarrhythmic efficacy of amiodarone treatment was examined in 196 patients
with recurrent ventricular tachycardia (VT) or ventricular fibrillation (VF) resistant to other …

Efficacy and safety of long-term amiodarone in treatment of cardiac arrhythmias: dosage experience

CI Haffajee, JC Love, JS Alpert, GK Asdourian… - American heart …, 1983 - Elsevier
The efficacy and safety of long-term oral amiodarone was assessed in 173 patients with
symptomatic tachyarrhythmias: 96 with life-threatening ventricular tachycardia and fibrillation …

Long-term results of amiodarone therapy in patients with recurrent sustained ventricular tachycardia or ventricular fibrillation

JM Herre, MJ Sauve, P Malone, JC Griffin… - Journal of the American …, 1989 - Elsevier
Four hundred sixty-two patients, all with either documented spontaneous sustained
ventricular tachycardia or cardiac arrest unresponsive to other antiarrhythmic drugs …

Beneficial effects of low dose amiodarone in patients with congestive cardiac failure: a placebo-controlled trial

AWF Hamer, LB Arkles, JA Johns - Journal of the American College of …, 1989 - Elsevier
The effects of amiodarone in a low dosage (200 mg every 8 h for 2 weeks, then 200 mg/day)
was assessed in a double-blind placebo-controlled trial in 34 patients with a history of …

Ten years of experience with amiodarone

MB Rosenbaum, PA Chiale, A Haedo, JO Lázzari… - American heart …, 1983 - Elsevier
Arrhythmias may be controlled in most patients with recurrent supraventricular tachycardia
or atrial fibrillation with small to moderate maintenance doses of amiodarone (100 to 400 …

Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia

SN Singh, RD Fletcher, SG Fisher… - … England Journal of …, 1995 - Mass Medical Soc
Background Asymptomatic ventricular arrhythmias in patients with congestive heart failure
are associated with increased rates of overall mortality and sudden death. Amiodarone is …