Chronic stress in rats has been shown to impair learning and memory, and precipitate
several affective disorders like depression and anxiety. The mechanisms involved in these …

Rationale Chronic stress results in cognitive impairment, affects hippocampal neurogenesis
and is known to precipitate affective disorders such as depression. In addition to stress …

Background: It is well known that intense and prolonged stress can produce cognitive
impairments and hippocampal damage and increase noradrenergic activity in humans. This …

Rationale In depressive disorders, one of the mechanisms proposed for antidepressant
drugs is the enhancement of synaptic plasticity in the hippocampus and cerebral cortex …

In this study, we investigated the effects of chronic stress procedure and moclobemide in
rats, and the influence of chronic stress on the levels of monoamines: noradrenaline (NE) …

Rationale Severe, traumatic stress or repeated exposure to stress can result in long-term
deleterious effects, including hippocampal cell atrophy and death, which, in turn, result in …

In the present study, we examined the effect of metyrapone, an inhibitor of corticosterone
(CS) synthesis, on the behavioral and neurochemical sequelae induced by a brief restraint …

Mild traumatic brain injuries (TBIs) comprise three-quarters of all TBIs occurring in the United
States annually, and psychological symptoms arising from them can last years after injury …

The first purpose of the present study was to investigate possible effects of predatory stress
(ie, 5-min cat exposure) on short-term learning abilities in Swiss mice using the object …

The immediate post-trial injection of the centrally active muscarinic agonist oxotremorine
(0.025, 0.050 and 0.100 mg/kg, IP) can facilitate the retention of a passiveavoidance …