A next generation sequencing gene panel for use in the diagnosis of anorexia nervosa

MR Ceccarini, V Precone, E Manara, S Paolacci… - Eating and Weight …, 2021 - Springer
Purpose The aim of this study was to increase knowledge of genes associated with anorexia
nervosa (AN) and their diagnostic offer, using a next generation sequencing (NGS) panel for …

[HTML][HTML] Genetic and epigenetic findings in anorexia nervosa

R Hirtz, A Hinney - Medizinische Genetik, 2020 - degruyter.com
Polygenic factors are relevant for the genetic predispositions to the eating disorder anorexia
nervosa (AN). The most recent genome-wide association study (GWAS) for AN comprised …

Genetic variants identified in novel candidate genes for anorexia nervosa and analysis of molecular pathways for diagnostic applications

K Donato, MC Medori, A Macchia… - European Review for …, 2023 - ricerca.unich.it
OBJECTIVE: Anorexia nervosa (AN) is a severe psychiatric disorder characterized by an
intense fear of gaining weight, a relentless pursuit of thinness, and a distorted body image …

The genetics of anorexia nervosa

TK Clarke, ARD Weiss… - Clinical Pharmacology & …, 2012 - Wiley Online Library
Anorexia nervosa (AN) is a disease defined by inappropriate weight loss and maintenance
of body weight< 85% of that expected for weight and height; it is most common in adolescent …

Association study of 182 candidate genes in anorexia nervosa

AP Pinheiro, CM Bulik, LM Thornton… - American Journal of …, 2010 - Wiley Online Library
We performed association studies with 5,151 SNPs that were judged as likely candidate
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …

Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment

S Paolacci, AK Kiani, E Manara… - Molecular genetics & …, 2020 - Wiley Online Library
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …

Overview of genetic research in anorexia nervosa: The past, the present and the future

MK Brandys, CGF de Kovel, MJ Kas… - … journal of eating …, 2015 - Wiley Online Library
Background Even though the evidence supporting the presence of a heritable component in
the aetiology of anorexia nervosa (AN) is strong, the underlying genetic mechanisms remain …

[HTML][HTML] The genetics of anorexia nervosa: current findings and future perspectives

AP Pinheiro, T Root, CM Bulik - International journal of child and …, 2009 - ncbi.nlm.nih.gov
Anorexia nervosa is a perplexing illness with the highest mortality rate of any psychiatric
disease. In this paper, we review the genetic research on anorexia nervosa (AN). Family …

Anorexia nervosa is associated with Neuronatin variants

L Lombardi, C Blanchet, K Poirier, N Lebrun… - Psychiatric …, 2019 - journals.lww.com
Background Anorexia nervosa is a complex neuropsychiatric disorder presenting with life-
threatening low body weight, and a persistent fear of gaining weight. To date, no whole …

Association of candidate genes with phenotypic traits relevant to anorexia nervosa

TL Root, JP Szatkiewicz, CR Jonassaint… - European Eating …, 2011 - Wiley Online Library
This analysis is a follow‐up to an earlier investigation of 182 genes selected as likely
candidate genetic variations conferring susceptibility to anorexia nervosa (AN). As those …