Controlled protein release from monodisperse biodegradable double-wall microspheres of controllable shell thickness

Y Xia, PF Ribeiro, DW Pack - Journal of controlled release, 2013 - Elsevier
Biodegradable polymer microparticles are promising delivery depots for protein therapeutics
due to their relatively simple fabrication and facile administration. Double-wall microspheres …

Protein encapsulation in and release from monodisperse double-wall polymer microspheres

Y Xia, Q Xu, C Wang, DW Pack - Journal of pharmaceutical sciences, 2013 - Elsevier
Biodegradable polymer double-wall microspheres (DWMS) are promising vehicles for
macromolecular therapeutics such as proteins and peptides. Using precision particle …

Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres

LE Kokai, H Tan, S Jhunjhunwala, SR Little… - Journal of Controlled …, 2010 - Elsevier
Double-walled microspheres present an improved drug delivery technique for sustained
release of encapsulated substrates. In this study, the release kinetics and biological activity …

[HTML][HTML] Uniform biodegradable microparticle systems for controlled release

Y Xia, DW Pack - Journal of controlled release: official journal of the …, 2002 - ncbi.nlm.nih.gov
Drug delivery methods can impact efficacy as much as the nature of the drug itself.
Microparticles made of biodegradable polymers such as poly (D, L-lactide-co-glycolide) and …

Uniform biodegradable microparticle systems for controlled release

Y Xia, DW Pack - Chemical Engineering Science, 2015 - Elsevier
Drug delivery methods can impact efficacy as much as the nature of the drug itself.
Microparticles made of biodegradable polymers such as poly (D, l-lactide-co-glycolide) and …

Osmogen‐Mediated One‐Step Technique of Fabricating Hollow Microparticles for Encapsulation and Delivery of Bioactive Molecules

S Kharel, WL Lee, XY Lee… - Macromolecular …, 2017 - Wiley Online Library
Microparticulate systems composed of biodegradable polymers, such as poly (d, l‐lactic‐co‐
glycolic acid)(PLGA), are widely used for controlled release of bioactive molecules …

Poly (ethylene glycol)-poly (lactic-co-glycolic acid) core–shell microspheres with enhanced controllability of drug encapsulation and release rate

C Cha, JH Jeong, H Kong - Journal of Biomaterials Science …, 2015 - Taylor & Francis
Poly (lactic-co-glycolic acid)(PLGA) microspheres have been widely used as drug carriers
for minimally invasive, local, and sustained drug delivery. However, their use is often …

Macromolecule release from monodisperse PLG microspheres: control of release rates and investigation of release mechanism

C Berkland, E Pollauf, C Raman, R Silverman… - Journal of …, 2007 - Elsevier
Novel macromolecular therapeutics such as peptides, proteins, and DNA are advancing
rapidly toward the clinic. Because of typically low oral bioavailability, macromolecule …

Recent advance in polymer based microspheric systems for controlled protein and peptide delivery

Y Yang, Q Chen, J Lin, Z Cai, G Liao… - Current medicinal …, 2019 - ingentaconnect.com
Sustained-release systems made by biodegradable polymers for protein and peptide drug
delivery have received considerable attention by academic researchers and major …

Pulsatile protein release from monodisperse liquid-core microcapsules of controllable shell thickness

Y Xia, DW Pack - Pharmaceutical research, 2014 - Springer
Purpose Pulsatile delivery of proteins, in which release occurs over a short time after a
period of little or no release, is desirable for many applications. This paper investigates the …