Sex-specific effects of sex steroids on alveolar epithelial Na+ transport
M Haase, M Laube, UH Thome - American Journal of …, 2017 - journals.physiology.org
Alveolar fluid clearance mediates perinatal lung transition to air breathing in newborn
infants, which is accomplished by epithelial Na+ channels (ENaC) and Na-K-ATPase. Male …
infants, which is accomplished by epithelial Na+ channels (ENaC) and Na-K-ATPase. Male …
[HTML][HTML] Male sex is associated with a reduced alveolar epithelial sodium transport
T Kaltofen, M Haase, UH Thome, M Laube - PloS one, 2015 - journals.plos.org
Respiratory distress syndrome (RDS) is the most frequent pulmonary complication in
preterm infants. RDS incidence differs between genders, which has been called the male …
preterm infants. RDS incidence differs between genders, which has been called the male …
[HTML][HTML] Glucocorticoids Equally Stimulate Epithelial Na+ Transport in Male and Female Fetal Alveolar Cells
M Laube, D Riedel, B Ackermann, M Haase… - International Journal of …, 2019 - mdpi.com
Preterm infants frequently suffer from respiratory distress syndrome (RDS), possibly due to
lower expression of epithelial Na+ channels (ENaC). RDS incidence is sex-specific …
lower expression of epithelial Na+ channels (ENaC). RDS incidence is sex-specific …
[HTML][HTML] Y It Matters—Sex differences in fetal lung development
M Laube, UH Thome - Biomolecules, 2022 - mdpi.com
Within this review, sex-specific differences in alveolar epithelial functions are discussed with
special focus on preterm infants and the respiratory disorders associated with premature …
special focus on preterm infants and the respiratory disorders associated with premature …
The interaction of glucocorticoids and progesterone distinctively affects epithelial sodium transport
C Schmidt, J Klammt, UH Thome, M Laube - Lung, 2014 - Springer
Purpose Glucocorticoids and progesterone exert stimulatory effects on epithelial Na+
transport, including increased mRNA expression of the participating ion transporters …
transport, including increased mRNA expression of the participating ion transporters …
[HTML][HTML] Epidermal growth factor strongly affects epithelial Na+ transport and barrier function in fetal alveolar cells, with minor sex-specific effects
M Laube, D Dornis, F Wenzel, UH Thome - Scientific Reports, 2021 - nature.com
Male sex remains an independent risk factor for respiratory distress syndrome (RDS) in
preterm infants. Insufficient Na+ transport-mediated alveolar fluid clearance contributes to …
preterm infants. Insufficient Na+ transport-mediated alveolar fluid clearance contributes to …
Postnatal gene expression of airway epithelial sodium transporters associated with birth stress in humans
L Süvari, C Janer, O Helve, A Kaskinen… - Pediatric …, 2019 - Wiley Online Library
Introduction Lung fluid clearance is essential for successful postnatal pulmonary adaptation.
The epithelial sodium channel (ENaC) and Na‐K‐ATPase, induced by serum‐and …
The epithelial sodium channel (ENaC) and Na‐K‐ATPase, induced by serum‐and …
[HTML][HTML] Modulation of sodium transport in alveolar epithelial cells by estradiol and progesterone
M Laube, E Küppers, UH Thome - Pediatric research, 2011 - nature.com
The effects of estradiol (E2) and progesterone (P) on alveolar epithelial Na+ transport were
studied in isolated alveolar epithelial cells from 18-to 19-d GA rat fetuses, grown to …
studied in isolated alveolar epithelial cells from 18-to 19-d GA rat fetuses, grown to …
Postnatal glucocorticoids induce α-ENaC formation and regulate glucocorticoid receptors in the preterm rabbit lung
SB Mustafa, RJ DiGeronimo… - … of Physiology-Lung …, 2004 - journals.physiology.org
At birth, lung fluid clearance is coupled to Na+ transport through epithelial Na+ channels
(ENaC) in the distal lung epithelium. We evaluated the effect of postnatal glucocorticoids …
(ENaC) in the distal lung epithelium. We evaluated the effect of postnatal glucocorticoids …
Salt and water transport across the alveolar epithelium in the developing lung: Correlations between function and recent molecular biology advances
HG Folkesson, A Norlin… - … Journal of Molecular …, 1998 - spandidos-publications.com
Significant progress have been made in understanding the mechanisms of alveolar fluid
clearance at the time of birth and the transition from placental oxygenation to air breathing …
clearance at the time of birth and the transition from placental oxygenation to air breathing …