Bright ideas for chemical biology
Small-molecule fluorescent probes embody an essential facet of chemical biology. Although
numerous compounds are known, the ensemble of fluorescent probes is based on a modest …
numerous compounds are known, the ensemble of fluorescent probes is based on a modest …
Bright building blocks for chemical biology
Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology.
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
As we noted in a previous review (Lavis, LD; Raines, RT ACS Chem. Biol. 2008, 3, 142 …
The chemistry of small-molecule fluorogenic probes
JB Grimm, LM Heckman, LD Lavis - Progress in molecular biology and …, 2013 - Elsevier
Chemical fluorophores find wide use in biology to detect and visualize different phenomena.
A key advantage of small-molecule dyes is the ability to construct compounds where …
A key advantage of small-molecule dyes is the ability to construct compounds where …
Rational design of small molecule fluorescent probes for biological applications
Fluorescent small molecules are powerful tools for visualizing biological events, embodying
an essential facet of chemical biology. Since the discovery of the first organic fluorophore …
an essential facet of chemical biology. Since the discovery of the first organic fluorophore …
Lessons in organic fluorescent probe discovery
Fluorescent probes have gained profound use in biotechnology, drug discovery, medical
diagnostics, molecular and cell biology. The development of methods for the translation of …
diagnostics, molecular and cell biology. The development of methods for the translation of …
Fluorogenic label for biomolecular imaging
Traditional small-molecule fluorophores are always fluorescent. This attribute can obscure
valuable information in biological experiments. Here, we report on a versatile “latent” …
valuable information in biological experiments. Here, we report on a versatile “latent” …
Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
The dynamic chemical diversity of elements, ions and molecules that form the basis of life
offers both a challenge and an opportunity for study. Small-molecule fluorescent probes can …
offers both a challenge and an opportunity for study. Small-molecule fluorescent probes can …
Fluorescent probes for sensing and imaging
T Ueno, T Nagano - Nature methods, 2011 - nature.com
Fluorescent probes for sensing and imaging | Nature Methods Skip to main content Thank you
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for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
Fluorescent probes for the detection of disease-associated biomarkers
WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …
biology and medicine. The ability to detect intracellular species and monitor physiological …
Advances in the chemistry of small molecule fluorescent probes
LM Wysocki, LD Lavis - Current opinion in chemical biology, 2011 - Elsevier
Small molecule fluorophores are essential tools for chemical biology. A benefit of synthetic
dyes is the ability to employ chemical approaches to control the properties and direct the …
dyes is the ability to employ chemical approaches to control the properties and direct the …