Abstract Purpose The prsA and vraTSR regulatory systems play a unique role in methicillin
resistance by modifying the peptidoglycan cell wall PBP2 and involving cell wall stress …

The psm-mec element and other regulatory factors such as sarA, agrA, and RNAIII are
responsible for maintaining the genetic framework for enhanced virulence of MRSA. psm …

Methicillin-resistant Staphylococcus aureus (MRSA) strains that are resistant to all forms of
penicillin have become an increasingly common and urgent problem threatening human …

Methicillin-resistant Staphylococcus aureus (MRSA), also known as oxacillin-resistant S.
aureus, is a leading cause of community and hospital associated infections globally. In this …

Abstract The World Health Organization (WHO) has defined Vancomycin intermediate
Staphylococcus aureus (VISA) and Vancomycin resistant Staphylococcus aureus (VRSA) as …

The objective of this study was to comprehensively identify the target genes regulated by the
two-component regulatory system VraSR in Staphylococcus aureus and to clarify the role of …

Transcriptional profiling of Staphylococcus aureus treated with cell wall-active antibiotics
identified the 2-component system, VraSR, as one of the key players in response to …

Staphylococcus aureus is an opportunistic pathogen that colonizes human hosts and
causes a wide variety of diseases. Two interacting regulatory systems called agr (accessory …

Methicillin/oxacillin (Oxa) resistance in Staphylococcus aureus is primarily mediated by the
acquired penicillin-binding protein (PBP2a) encoded by mecA. PBP2a acts together with …

Abstract The World Health Organization (WHO) has defined Vancomycin intermediate
Staphylococcus aureus (VISA) and Vancomycin resistant Staphylococcus aureus (VRSA) as …