Examining overlap and homogeneity in ASD, ADHD, and OCD: a data-driven, diagnosis-agnostic approach

A Kushki, E Anagnostou, C Hammill, P Duez… - Translational …, 2019 - nature.com
The validity of diagnostic labels of autism spectrum disorder (ASD), attention-
deficit/hyperactivity disorder (ADHD), and obsessive compulsive disorder (OCD) is an open …

Toward neurosubtypes in autism

SJ Hong, JT Vogelstein, A Gozzi, BC Bernhardt… - Biological …, 2020 - Elsevier
There is a consensus that substantial heterogeneity underlies the neurobiology of autism
spectrum disorder (ASD). As such, it has become increasingly clear that a dissection of …

Structural brain measures among children with and without ADHD in the Adolescent Brain and Cognitive Development Study cohort: a cross-sectional US population …

J Bernanke, A Luna, L Chang, E Bruno… - The Lancet …, 2022 - thelancet.com
Background Structural neuroimaging research has identified a variety of abnormalities in
cortical and subcortical structures in children with ADHD. However, studies to date have not …

From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder

T Wolfers, DL Floris, R Dinga, D van Rooij… - Neuroscience & …, 2019 - Elsevier
Pattern classification and stratification approaches have increasingly been used in research
on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation …

Subtyping attention-deficit/hyperactivity disorder using temperament dimensions: toward biologically based nosologic criteria

SL Karalunas, D Fair, ED Musser, K Aykes… - JAMA …, 2014 - jamanetwork.com
Importance Psychiatric nosology is limited by behavioral and biological heterogeneity within
existing disorder categories. The imprecise nature of current nosologic distinctions limits …

Classification accuracy of neuroimaging biomarkers in attention-deficit/hyperactivity disorder: effects of sample size and circular analysis

AA Pulini, WT Kerr, SK Loo, A Lenartowicz - … : Cognitive Neuroscience and …, 2019 - Elsevier
Background Motivated by an inconsistency between reports of high diagnosis-classification
accuracies and known heterogeneity in attention-deficit/hyperactivity disorder (ADHD), this …

Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD

DA Fair, D Bathula, MA Nikolas… - Proceedings of the …, 2012 - National Acad Sciences
Research and clinical investigations in psychiatry largely rely on the de facto assumption
that the diagnostic categories identified in the Diagnostic and Statistical Manual (DSM) …

[HTML][HTML] Reconciling dimensional and categorical models of autism heterogeneity: a brain connectomics and behavioral study

S Tang, N Sun, DL Floris, X Zhang, A Di Martino… - Biological …, 2020 - Elsevier
Background Heterogeneity in autism spectrum disorder (ASD) has hindered the
development of biomarkers, thus motivating subtyping efforts. Most subtyping studies divide …

Progress and roadblocks in the search for brain-based biomarkers of autism and attention-deficit/hyperactivity disorder

LQ Uddin, DR Dajani, W Voorhies, H Bednarz… - Translational …, 2017 - nature.com
Children with neurodevelopmental disorders benefit most from early interventions and
treatments. The development and validation of brain-based biomarkers to aid in objective …

Diagnostic classification for human autism and obsessive-compulsive disorder based on machine learning from a primate genetic model

Y Zhan, J Wei, J Liang, X Xu, R He… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Psychiatric disorders commonly comprise comorbid symptoms, such as autism
spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and attention deficit …