Primary liver cancer, consisting predominantly of hepatocellular carcinoma (HCC) and
cholangiocarcinoma (CCA), remains one of the most lethal malignancies worldwide. This …

Organoid culture is an emerging research tool that has proved tremendously useful in a
multitude of aspects, one of which is cancer research. They largely overcome the limitations …

The current understanding of cancer biology and development of effective treatments for
cancer remain far from satisfactory. This in turn heavily relies on the availability of easy and …

Gastrointestinal (GI) cancers constitute the largest portion of all human cancers and
represent a significant health burden on modern society. Conventional therapeutic …

Primary liver cancer (PLC) is the second leading cause of cancer mortality worldwide, and
its morbidity unceasingly increases these years. Hepatitis B virus (HBV) infection accounted …

Primary liver cancers (PLC), including hepatocellular carcinoma (HCC) and
cholangiocarcinoma (CCA), are among the leading causes of cancer-related mortality …

Simple Summary Despite remarkable progress in the treatment of cancer patients, the
medical need for drugs with better efficacy is still unmet and high. In addition to accurate …

Primary liver cancer (PLC) is the sixth most common tumour disease and one of the leading
causes of cancer-related death worldwide. The two most common types of PLC are …

Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …

Human liver cancer research currently lacks in vitro models that can faithfully recapitulate
the pathophysiology of the original tumor. We recently described a novel, near-physiological …