Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity

A Omolu, M Bailly, RM Day - Drug delivery, 2017 - Taylor & Francis
Many chronic wounds exhibit high matrix metalloproteinase (MMP) activity that impedes the
normal wound healing process. Intradermal delivery (IDD) of sub-antimicrobial …

[PDF][PDF] Microneedles for transdermal drug delivery: a minireview

J Vandervoort, A Ludwig - Front Biosci, 2008 - article.imrpress.com
[Frontiers in Bioscience 13, 1711-1715, January 1, 2008] 1711 Microneedles for transdermal
drug delivery: a minireview Jo Vande Page 1 [Frontiers in Bioscience 13, 1711-1715, January …

A microneedle roller for transdermal drug delivery

JH Park, SO Choi, S Seo, YB Choy… - European journal of …, 2010 - Elsevier
Microneedle rollers have been used to treat large areas of skin for cosmetic purposes and to
increase skin permeability for drug delivery. In this study, we introduce a polymer …

Microneedle technologies for (trans) dermal drug and vaccine delivery

K Van Der Maaden, W Jiskoot, J Bouwstra - Journal of controlled release, 2012 - Elsevier
Microneedles have been used for the dermal and transdermal delivery of a broad range of
drugs, such as small molecular weight drugs, oligonucleotides, DNA, peptides, proteins and …

Microneedles: A versatile strategy for transdermal delivery of biological molecules

DJ Lim, JB Vines, H Park, SH Lee - International journal of biological …, 2018 - Elsevier
Human skin is made up of multiple layers and is designed to protect the human body. The
stratum corneum (SC), specifically, is a keratinized layer of skin through which molecules …

Poly (vinyl alcohol) microneedles: Fabrication, characterization, and application for transdermal drug delivery of doxorubicin

HX Nguyen, BD Bozorg, Y Kim, A Wieber, G Birk… - European journal of …, 2018 - Elsevier
Poly (vinyl alcohol) microneedles were fabricated, characterized, and applied to enhance in
vitro transdermal delivery of doxorubicin. The microneedles were fabricated using the …

Microneedle-based drug delivery: studies on delivery parameters and biocompatibility

Y Wu, Y Qiu, S Zhang, G Qin, Y Gao - Biomedical microdevices, 2008 - Springer
There is a significant interest in the application of microneedles in intradermal drug delivery
systems. Previous studies have demonstrated that skin permeation of drugs can be …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Microneedle-mediated transdermal and intradermal drug delivery

RF Donnelly, TRR Singh, DIJ Morrow, AD Woolfson - 2012 - books.google.com
Microneedles can be used for delivery of a wide range of drug substances for practically any
medical condition and present a real opportunity for vaccines and medicines that are …

Microneedles: an emerging transdermal drug delivery system

SH Bariya, MC Gohel, TA Mehta… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives One of the thrust areas in drug delivery research is transdermal drug delivery
systems (TDDS) due to their characteristic advantages over oral and parenteral drug …