Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

L Duncan, Z Yilmaz, H Gaspar… - American journal of …, 2017 - Am Psychiatric Assoc
Objective: The authors conducted a genome-wide association study of anorexia nervosa
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …

Association study of 182 candidate genes in anorexia nervosa

AP Pinheiro, CM Bulik, LM Thornton… - American Journal of …, 2010 - Wiley Online Library
We performed association studies with 5,151 SNPs that were judged as likely candidate
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …

Linkage analysis of anorexia nervosa incorporating behavioral covariates

B Devlin, SA Bacanu, KL Klump… - Human Molecular …, 2002 - academic.oup.com
Eating disorders, such as anorexia nervosa (AN) and bulimia nervosa (BN), have genetic
and environmental underpinnings. To explore genetic contributions to AN, we measured …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

HJ Watson, Z Yilmaz, LM Thornton, C Hübel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …

Genetics of anorexia nervosa

JH Baker, K Schaumberg, MA Munn-Chernoff - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review Genetic factors contribute to the etiology of anorexia nervosa
(AN). This review synthesizes the current state of knowledge about the genetic etiology of …

A genome-wide association study of anorexia nervosa

V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa

C Hübel, HA Gaspar, JRI Coleman… - American Journal of …, 2019 - Wiley Online Library
Anorexia nervosa (AN) occurs nine times more often in females than in males. Although
environmental factors likely play a role, the reasons for this imbalanced sex ratio remain …

Genetic variants associated with disordered eating

TD Wade, S Gordon, S Medland… - … Journal of Eating …, 2013 - Wiley Online Library
Objective Although the genetic contribution to the development of anorexia nervosa (AN)
has long been recognized, there has been little progress relative to other psychiatric …

A search for susceptibility loci for anorexia nervosa: methods and sample description

WH Kaye, LR Lilenfeld, WH Berrettini, M Strober… - Biological …, 2000 - Elsevier
Background: Eating disorders have not traditionally been viewed as heritable illnesses;
however, recent family and twin studies lend credence to the potential role of genetic …

Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder

Z Yilmaz, M Halvorsen, J Bryois, D Yu… - Molecular …, 2020 - nature.com
Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) are often comorbid and
likely to share genetic risk factors. Hence, we examine their shared genetic background …