Effects of adenosine A2a receptor agonist and antagonist on hippocampal nuclear factor-kB expression preceded by MDMA toxicity

F Kermanian, M Soleimani, A Ebrahimzadeh… - Metabolic brain …, 2013 - Springer
There is an abundance of evidence showing that repeated use of 3, 4-
methlylenedioxymethamphetamine (MDMA; ecstasy) is associated with brain dysfunction …

[HTML][HTML] Effects of adenosine A2a receptor agonist and antagonist on cerebellar nuclear factor-kB expression preceded by MDMA toxicity

F Kermanian, M Soleimani, B Pourheydar… - Medical Journal of the …, 2014 - ncbi.nlm.nih.gov
Background: Adenosine is an endogenous purine nucleoside that has a neuromodulatory
role in the central nervous system. The amphetamine derivative (±)-3, 4 …

The role of adenosine receptor agonist and antagonist on Hippocampal MDMA detrimental effects; a structural and behavioral study

F Kermanian, M Mehdizadeh, M Soleimani… - Metabolic brain …, 2012 - Springer
There is abundant evidence showing that repeated use of MDMA (3, 4-
Methylenedioxymethamphetamine, ecstasy) has been associated with depression, anxiety …

MDMA related neuro-inflammation and adenosine receptors

F Kermanian, M Seghatoleslam… - Neurochemistry …, 2022 - Elsevier
methylenedioxymethamphetamine (MDMA) is a world-wide abused psychostimulant, which
has the neurotoxic effects on dopaminergic and serotonergic neurons in both rodents and …

MDMA administration decreases serotonin but not N-acetylaspartate in the rat brain

SA Perrine, F Ghoddoussi, MS Michaels, EM Hyde… - Neurotoxicology, 2010 - Elsevier
In animals, repeated administration of 3, 4-methylenedioxymethamphetamine (MDMA)
reduces markers of serotonergic activity and studies show similar serotonergic deficits in …

The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA

J Ruiz-Medina, C Ledent, O Carretón… - Journal of …, 2011 - journals.sagepub.com
Adenosine is an endogenous purine nucleoside that plays a neuromodulatory role in the
central nervous system. A2a adenosine receptors have been involved in reward-related …

[HTML][HTML] The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum

AM Górska, K Gołembiowska - Neurotoxicity research, 2015 - Springer
Methylenedioxymethamphetamine (MDMA,“ecstasy”) popular as a designer drug is often
used with caffeine to gain a stronger stimulant effect. MDMA induces 5-HT and DA release …

Attenuation of ecstasy-induced neurotoxicity by N-acetylcysteine

S Soleimani Asl, B Saifi, A Sakhaie… - Metabolic brain …, 2015 - Springer
Abstract Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) can lead to spatial
memory impairments and hippocampal cell death. Numerous evidence indicates that the …

[HTML][HTML] Acute MDMA and nicotine co-administration: behavioral effects and oxidative stress processes in mice

B Budzynska, A Wnorowski, K Kaszubska… - Frontiers in behavioral …, 2018 - frontiersin.org
3, 4-Methylenedioxy-methylamphetamine (MDMA), a synthetic substance commonly known
as ecstasy, is a worldwide recreational drug of abuse. As MDMA and nicotine activate the …

NMDA depresses glutamatergic synaptic transmission in the striatum through the activation of adenosine A1 receptors: evidence from knockout mice

SM Schotanus, BB Fredholm, K Chergui - Neuropharmacology, 2006 - Elsevier
N-methyl-d-aspartate (NMDA) receptors play several essential roles in the physiology and
pathophysiology of the brain. Their activation results in long-term changes in glutamatergic …