pharmacological aspects of anti‐TNF biosimilars in inflammatory bowel diseases

K Papamichael, T Van Stappen… - Alimentary …, 2015 - Wiley Online Library
Background Anti‐tumour necrosis factor (anti‐TNF) monoclonal antibodies have shown
efficacy in inflammatory bowel diseases (IBD). As these therapies lose patent protection …

Systematic review with meta‐analysis: the efficacy and safety of CT‐P13, a biosimilar of anti‐tumour necrosis factor‐α agent (infliximab), in inflammatory bowel …

Y Komaki, A Yamada, F Komaki, D Micic… - Alimentary …, 2017 - Wiley Online Library
Background Biosimilars of anti‐tumour necrosis factor (TNF)‐α agents have now become
clinically available for the treatment of inflammatory bowel diseases (IBD). Aim To perform a …

Infliximab biosimilars in the treatment of inflammatory bowel diseases: a systematic review

M Radin, S Sciascia, D Roccatello, MJ Cuadrado - BioDrugs, 2017 - Springer
Background Biological therapies represent a fundamental innovation for the management of
inflammatory bowel diseases (IBD). However, many biological originators have reached, or …

Efficacy, safety and immunogenicity of biosimilars in inflammatory bowel diseases: A systematic review

L Martelli, L Peyrin-Biroulet - Current Medicinal Chemistry, 2019 - ingentaconnect.com
Background: Anti-tumor necrosis factor (anti-TNF) monoclonal antibodies have
revolutionized the treatment of inflammatory bowel diseases (IBD). However, because of …

Biosimilars in the therapy of inflammatory bowel diseases

T Hlavaty, J Letkovsky - European journal of gastroenterology & …, 2014 - journals.lww.com
A biosimilar is a copy of an approved biological medicine whose patent protections have
expired. Biosimilars of antibodies to tumour necrosis factor α (TNFα) are becoming important …

Progress with infliximab biosimilars for inflammatory bowel disease

Z Kurti, L Gonczi, PL Lakatos - Expert Opinion on Biological …, 2018 - Taylor & Francis
Introduction: Biological therapies have revolutionized the treatment of inflammatory bowel
diseases (IBD) in the last two decades. Though biological drugs are effective, their use is …

Use of biosimilars in inflammatory bowel disease: statements of the Italian group for inflammatory bowel disease

V Annese, M Vecchi, F Bossa, E Calabrese… - Digestive and Liver …, 2014 - Elsevier
The introduction of biological therapies, particularly anti-TNFα agents, has revolutionized the
management of inflammatory bowel disease in those cases which are refractory to …

Efficacy and safety of CT‐P13, a biosimilar of infliximab, in patients with inflammatory bowel disease: A retrospective multicenter study

YS Jung, DI Park, YH Kim, JH Lee… - Journal of …, 2015 - Wiley Online Library
Abstract Background and Aim The biosimilar of infliximab, CT‐P13, has recently been
shown to be equivalent to infliximab in both efficacy and safety in the treatment of …

[HTML][HTML] Current status of biosimilars in the treatment of inflammatory bowel diseases

DI Park - Intestinal research, 2016 - ncbi.nlm.nih.gov
Introduction of biological therapies have led to dramatic changes in the management of
debilitating immune-mediated inflammatory bowel diseases (IBD) including ulcerative colitis …

TNF-alpha blockers in inflammatory bowel diseases: practical recommendations and a user's guide: an update

M Vulliemoz, S Brand, P Juillerat, C Mottet… - Digestion, 2020 - karger.com
Background: Anti-tumour necrosis factor-alpha (anti-TNF) antagonists have been the
mainstay in the treatment of inflammatory bowel diseases (IBDs) for over 20 years …