Prospective randomized trial of venous angioplasty in MS (PREMiSe)

AH Siddiqui, R Zivadinov, RHB Benedict, Y Karmon… - Neurology, 2014 - AAN Enterprises
Objective: We report the results of the investigation of safety and efficacy of venous
angioplasty in patients with multiple sclerosis (MS) with findings of extracranial venous …

Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …

Effects of venous angioplasty on cerebral lesions in multiple sclerosis: expanded analysis of the brave dreams double-blind, sham-controlled randomized trial

P Zamboni, R Galeotti, F Salvi… - Journal of …, 2020 - journals.sagepub.com
Purpose: To evaluate if jugular vein flow restoration in various venographic defects
indicative of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) …

[HTML][HTML] Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple …

P Zamboni, A Bertolotto, P Boldrini, P Cenni… - Trials, 2012 - Springer
Background Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system with a disabling progressive course. Chronic cerebrospinal venous …

[HTML][HTML] Venous angioplasty in patients with multiple sclerosis: results of a pilot study

P Zamboni, R Galeotti, B Weinstock-Guttman… - European Journal of …, 2012 - Elsevier
OBJECTIVES: Chronic cerebrospinal venous insufficiency (CCSVI) is associated with
multiple sclerosis (MS). The objective of the study was to see if percutaneous transluminal …

“Liberation treatment” for chronic cerebrospinal venous insufficiency in multiple sclerosis: the truth will set you free

G Tsivgoulis, S Faissner, K Voumvourakis… - Brain and …, 2015 - Wiley Online Library
Background Chronic cerebrospinal venous insufficiency (CCSVI) has recently been
introduced as a chronic state of impaired cerebral or cervical venous drainage that may be …

[HTML][HTML] Venous angioplasty in multiple sclerosis: neurological outcome at two years in a cohort of relapsing-remitting patients

F Salvi, I Bartolomei, E Buccellato, R Galeotti… - Functional …, 2012 - ncbi.nlm.nih.gov
Venous angioplasty in multiple sclerosis: neurological outcome at two years in a cohort of
relapsing-remitting patients - PMC Back to Top Skip to main content NIH NLM Logo Access …

Endovascular treatment of chronic cerebrospinal venous insufficiency in multiple sclerosis: a retrospective study

R Alroughani, S Lamdhade… - International Journal of …, 2013 - Taylor & Francis
Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed to be
associated with multiple sclerosis (MS). Zamboni et al. reported significant improvement in …

Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency in people with multiple sclerosis: a summary of a Cochrane …

EJ van Zuuren, Z Fedorowicz, E Pucci… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background It has been recently hypothesised that chronic cerebrospinal venous
insufficiency (CCSVI) may be an important factor in the pathogenesis of multiple sclerosis …

Extracranial venous angioplasty is ineffective to treat MS

R Zivadinov, B Weinstock-Guttman - Nature Reviews Neurology, 2018 - nature.com
A randomized, double-blind, sham-controlled trial, Brave Dreams, has shown no clinical or
radiological benefit of percutaneous transluminal angioplasty (PTA) to correct chronic …