Sexually transmitted infections are a critical public health issue. However, the mechanisms
underlying sexually transmitted infections in women and the link between the infection …

Neisseria gonorrhoeae (GC) establishes infection in women from the cervix, lined with
heterogeneous epithelial cells from non-polarized stratified at the ectocervix to polarized …

Infection and disease associated with Neisseria gonorrhoeae, the gonococcus, continue to
be a global health problem. Asymptomatic and subclinical gonococcal infections occur at a …

Chlamydia trachomatis (Ct) and Neisseria gonorrhoeae (Ng) are the most common bacterial
sexually transmitted infections (STIs) worldwide. The primary site of infection for both …

Gonorrhea is the second most common sexually transmitted infection, which is primarily
localized but can be disseminated systemically. The mechanisms by which a localized …

Several microbial pathogens can modulate the host apoptotic response to infection, which
may contribute to immune evasion. Various studies have reported that infection with the …

The gonococcal Opa proteins are an antigenically variable family of surface adhesins that
bind human carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) …

Pathogenic microorganisms, such as Neisseria gonorrhoeae, have developed mechanisms
to alter epithelial barriers in order to reach subepithelial tissues for host colonization. The …

The gonococcal Opa proteins are an antigenically variable family of surface adhesins that
bind 27 human CEACAM1, CEACAM3, CEACAM5 and/or CEACAM6, cell surface …

Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection
gonorrhoea, adheres to and invades into genital epithelial cells. Here, we investigate host …