Genetic regulation of fluxes: iron homeostasis of Escherichia coli

S Semsey, AMC Andersson, S Krishna… - Nucleic acids …, 2006 - academic.oup.com
Iron is an essential trace-element for most organisms. However, because high concentration
of free intracellular iron is cytotoxic, cells have developed complex regulatory networks that …

RyhB small RNA modulates the free intracellular iron pool and is essential for normal growth during iron limitation in Escherichia coli

JF Jacques, S Jang, K Prévost… - Molecular …, 2006 - Wiley Online Library
The small RNA RyhB has recently been shown to negatively regulate a number of mRNAs
encoding dispensable iron‐using proteins in Escherichia coli. The resulting decrease in the …

Effect of RyhB Small RNA on Global Iron Use in Escherichia coli

E Massé, CK Vanderpool, S Gottesman - Journal of bacteriology, 2005 - Am Soc Microbiol
RyhB is a noncoding RNA regulated by the Fur repressor. It has previously been shown to
cause the rapid degradation of a number of mRNAs that encode proteins that utilize iron …

A regulatory circuit composed of a transcription factor, IscR, and a regulatory RNA, RyhB, controls Fe-S cluster delivery

P Mandin, S Chareyre, F Barras - MBio, 2016 - Am Soc Microbiol
Fe-S clusters are cofactors conserved through all domains of life. Once assembled by
dedicated ISC and/or SUF scaffolds, Fe-S clusters are conveyed to their apo-targets via A …

Iron transport and metabolism in Escherichia, Shigella, and Salmonella

AR Mey, C Gómez-Garzón, SM Payne - EcoSal Plus, 2021 - Am Soc Microbiol
Iron is an essential element for Escherichia, Salmonella, and Shigella species. The
acquisition of sufficient amounts of iron is difficult in many environments, including the …

Damped oscillations in the adaptive response of the iron homeostasis network of E. coli

A Amir, S Meshner, T Beatus… - Molecular …, 2010 - Wiley Online Library
Living organisms often have to adapt to sudden environmental changes and reach
homeostasis. To achieve adaptation, cells deploy motifs such as feedback in their genetic …

Small RNAs controlling iron metabolism

E Masse, H Salvail, G Desnoyers, M Arguin - Current opinion in …, 2007 - Elsevier
Iron is one of the most important metals in the metabolism of many organisms, including
bacteria, in which it serves as a cofactor in multiple enzymatic reactions. Most of the earlier …

Ironing out the problem: new mechanisms of iron homeostasis

E Massé, M Arguin - Trends in biochemical sciences, 2005 - cell.com
For most organisms, iron is an essential nutrient that is both difficult to acquire from the
environment and toxic at high concentration. Therefore, to avoid deprivation or over …

[HTML][HTML] Global iron-dependent gene regulation in Escherichia coli: a new mechanism for iron homeostasis

JP McHugh, F Rodríguez-Quinoñes… - Journal of Biological …, 2003 - ASBMB
Organisms generally respond to iron deficiency by increasing their capacity to take up iron
and by consuming intracellular iron stores. Escherichia coli, in which iron metabolism is …

Iron-responsive bacterial small RNAs: variations on a theme

AG Oglesby-Sherrouse, ER Murphy - Metallomics, 2013 - academic.oup.com
For most living organisms, iron is both essential and potentially toxic, making the precise
maintenance of iron homeostasis necessary for survival. To manage this paradox, bacteria …