Oxidative stress can contribute to the development of diseases, and may originate from
exposures to toxicants commonly found in air pollution and cigarette smoke such as …

Objective: To evaluate the effect of cigarette smoking on oxidative and nitrosative stress, we
assessed urinary levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), isoprostane 15-F2t …

Cigarette smoking predisposes to the development of multiple diseases involving oxidative
damage. We measured a range of oxidative damage biomarkers to understand which differ …

Introduction Cross-sectional studies have consistently shown an association between
current smoking and oxidative stress biomarkers. However, no longitudinal studies have …

Chronic obstructive pulmonary disease (COPD) is a disease characterized by chronic
inflammation and irreversible airway obstruction. Cigarette smoking is the predominant risk …

Background: The objective of this study was to obtain baseline data on biomarkers of
exposure (BoE) and biomarkers of potential harm (BoPH) in smokers, former smokers and …

7, 8-Dihydro-8-oxo-2′-deoxyguanosine (8-oxo-dGuo) is a useful biomarker of oxidative
stress. However, its analysis can be challenging because 8-oxo-dGuo must be quantified in …

In a previous study, evidence was provided that indoor secondhand tobacco smoke (SHS)
air pollution remains high in Lisbon restaurants where smoking is allowed, regardless of the …

Background: Cigarette smoking is a risk factor for several diseases, including cardiovascular
disease, chronic obstructive pulmonary disease, and lung cancer, but the role of specific …

We determined the persistence at various times (3, 7, 14, 21, 28, 42, and 56 days) of eight
tobacco smoke carcinogen and toxicant biomarkers in the urine of 17 smokers who stopped …