The frequency of combined IFITM3 haplotype involving the reference alleles of both rs12252 and rs34481144 is in line with COVID-19 standardized mortality ratio of …

D Nikoloudis, D Kountouras, A Hiona - PeerJ, 2020 - peerj.com
Evidence was brought forward in England and the USA that Black, Asian, Latino and
Minority Ethnic people exhibit higher mortality risk from COVID-19 than White people. While …

[HTML][HTML] Association between the interferon-induced transmembrane protein 3 gene (IFITM3) rs34481144/rs12252 haplotypes and COVID-19

E Cuesta-Llavona, GM Albaiceta… - Current Research in …, 2021 - Elsevier
The interferon induced transmembrane-protein 3 (IFITM3) plays an important role in the
defence against viral infection. IFITM3 gene variants have been linked to differences in …

Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant

M Gholami, F Sakhaee, F Sotoodehnejadnematalahi… - Human Genomics, 2022 - Springer
Background The interferon-induced transmembrane-protein 3 (IFITM3) is a vital component
of the immune system's defense against viral infection. Variants in the IFITM3 gene have …

[HTML][HTML] Interferon-induced transmembrane protein-3 genetic variant rs12252 is associated with COVID-19 mortality

J Alghamdi, M Alaamery, T Barhoumi, M Rashid… - Genomics, 2021 - Elsevier
Interferon-induced membrane proteins (IFITM) 3 gene variants are known risk factor for
severe viral diseases. We examined whether IFITM3 variant may underlie the …

IFITM3 inhibits SARS-CoV-2 infection and is associated with COVID-19 susceptibility

F Xu, G Wang, F Zhao, Y Huang, Z Fan, S Mei, Y Xie… - Viruses, 2022 - mdpi.com
SARS-CoV-2 has become a global threat to public health. Infected individuals can be
asymptomatic or develop mild to severe symptoms, including pneumonia, respiratory …

The influence of IFITM3 polymorphisms on susceptibility to SARS-CoV-2 infection and severity of COVID-19

K Schönfelder, K Breuckmann, C Elsner, U Dittmer… - Cytokine, 2021 - Elsevier
Background and aims The interferon-induced transmembrane protein 3 (IFITM3) plays an
important role in the adaptive and innate immune response by inhibiting viral membrane …

The Interferon-induced transmembrane protein 3 gene (IFITM3) rs12252 C variant is associated with COVID-19

J Gómez, GM Albaiceta, E Cuesta-Llavona… - Cytokine, 2021 - Elsevier
Background and aims The interferon-induced transmembrane proteins play an important
antiviral role by preventing viruses from traversing the cellular lipid bilayer. IFITM3 gene …

[HTML][HTML] Interferon-induced transmembrane protein 3 rs34481144 C/T genotype and clinical parameters related to progression of COVID-19

M Gholami, F Sakhaee, F Mirzaei Gheinari… - Journal of Immunology …, 2023 - hindawi.com
Recent research has associated the interferon-induced transmembrane protein 3 gene
(IFITM3) with the outcomes of coronavirus disease 2019 (COVID-19), although the findings …

Impact of interferon-induced transmembrane protein 3 gene rs12252 polymorphism on COVID-19 mortality

I Ahmadi, A Afifipour, F Sakhaee, MS Zamani… - Cytokine, 2022 - Elsevier
Background and aims Interferon-induced transmembrane protein 3 (IFITM3) plays a critical
role in the adaptive and innate immune response by preventing membrane hemifusion …

Interferon-induced transmembrane protein 3 gene polymorphisms are associated with COVID-19 susceptibility and severity: a meta-analysis

Y Li, L Wei, L He, J Sun, N Liu - Journal of Infection, 2022 - Elsevier
Background Recent evidence has linked the interferon-induced transmembrane protein 3
gene (IFITM3) to coronavirus disease 2019 (COVID-19) outcomes, but the results are …