Rationale and design of the third vasodilator-heart failure trial (V-HeFT III): Felodipine as adjunctive therapy to enalapril and loop diuretics with or without digoxin in …

WE Boden, S Ziesche, PE Carson, CH Conrad… - The American journal of …, 1996 - Elsevier
Therapy with angiotensin-converting enzyme inhibitors and nonselective vasodilators
(hydralazine and isosorbide dinitrate) has become accepted treatment in patients with …

Vasodilators in heart failure: conclusions from V-HeFT II and rationale for V-HeFT III

JN Cohn - Drugs, 1994 - Springer
Summary The Veterans Affairs Vasodilator-Heart Failure Trials (V-HeFT I and II) provided
information about heart failure treated with conventional therapy, and evaluated the long …

[HTML][HTML] A comparison of enalapril with hydralazine–isosorbide dinitrate in the treatment of chronic congestive heart failure

JN Cohn, G Johnson, S Ziesche, F Cobb… - … England Journal of …, 1991 - Mass Medical Soc
Abstract Background and Methods. To define better the efficacy of vasodilator therapy in the
treatment of chronic congestive heart failure, we compared the effects of hydralazine and …

Assessing the treatment of congestive heart failure: diuretics, vasodilators, and angiotensin‐converting enzyme inhibitors

MSS Chow - … : The Journal of Human Pharmacology and Drug …, 1993 - Wiley Online Library
Congestive heart failure (CHF) causes disabling symptoms and increases the likelihood of
decreased survival. Diuretics, direct vasodilators, and angiotensin‐converting enzyme …

Effect of the calcium antagonist felodipine as supplementary vasodilator therapy in patients with chronic heart failure treated with enalapril: V-HeFT III

JN Cohn, S Ziesche, R Smith, I Anand, WB Dunkman… - Circulation, 1997 - Am Heart Assoc
Background Despite therapy with diuretics, ACE inhibitors and digoxin morbidity and
mortality in heart failure remain high and might respond favorably to an additional …

Placebo controlled trial of felodipine in patients with mild to moderate heart failure. UK Study Group.

WA Littler, DJ Sheridan - Heart, 1995 - heart.bmj.com
OBJECTIVE--To compare the effects of felodipine and placebo in patients with New York
Heart Association functional class II or III and stable congestive heart failure despite …

The treatment of heart failure: a methodological review of the literature

GH Guyatt - Drugs, 1986 - Springer
In this article literature concerning the major drugs used in the treatment of heart failure is
reviewed. Because of major discrepancies in results from short term and uncontrolled …

Overview of the treatment of heart failure

JN Cohn - The American journal of cardiology, 1997 - Elsevier
Short-term goals of heart failure management are directed toward relieving symptoms such
as shortness of breath, decreased exercise tolerance, and lower-extremity edema and …

Assessing the treatment of congestive heart failure: inotropic agents and calcium channel blockers

DE Hilleman - … : The Journal of Human Pharmacology and Drug …, 1993 - Wiley Online Library
Despite recent evidence that angiotensin‐converting enzyme (ACE) inhibitors reduce
mortality in patients with congestive heart failure (CHF), it is important to note that roughly …

Safety and efficacy study of delapril versus enalapril in patients with congestive heart failure

S Dalla-Volta - The American Journal of Cardiology, 1995 - Elsevier
The results after the first 6 months of the 1-year treatment of this multicenter, randomized,
open, parallel-group design study of delapril versus enalapril in patients with congestive …